TY - JOUR
T1 - Evaluation of chronic inflammatory demyelinating polyneuropathy
T2 - 3D nerve-sheath signal increased with inked rest-tissue rapid acquisition of relaxation enhancement imaging (3D SHINKEI)
AU - Hiwatashi, Akio
AU - Togao, Osamu
AU - Yamashita, Koji
AU - Kikuchi, Kazufumi
AU - Ogata, Hidenori
AU - Yamasaki, Ryo
AU - Yoneyama, Masami
AU - Kira, Jun ichi
AU - Honda, Hiroshi
N1 - Funding Information:
The scientific guarantor of this publication is Hiroshi Honda. The authors of this manuscript declare relationships with the following companies: Philips Electronics Japan. The authors state that this work was supported by JSPS KAKENHI Grant Number 26461826. Mr. Junji Kishimoto kindly provided statistical advice for this manuscript. Institutional Review Board approval was obtained. Written informed consent was waived by the Institutional Review Board. Some study subjects or cohorts have been previously reported at ASNR 2015. Methodology: retrospective, observational, performed at one institution.
Publisher Copyright:
© 2016, European Society of Radiology.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - Objective: To evaluate the usefulness of 3D nerve-sheath signal increased with inked rest-tissue rapid acquisition of relaxation enhancement imaging (SHINKEI) in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods: This institutional review board-approved retrospective study included 14 CIDP patients and nine normal subjects. The signal-to-noise ratio (SNR), contrast ratio (CR), and the size of the cervical ganglions and roots were measured by two raters. Results: The SNRs of the ganglions and roots were larger in patients with CIDP (9.55 ± 3.87 and 9.81 ± 3.64) than in normal subjects (7.21 ± 2.42 and 5.70 ± 2.14, P < 0.0001, respectively). The CRs of the ganglions and roots were larger in patients with CIDP (0.77 ± 0.08 and 0.68 ± 0.12) than in normal subjects (0.72 ± 0.07 and 0.53 ± 0.11, P < 0.0001, respectively). The sizes of the ganglions and the roots were larger in patients with CIDP (6.44 ± 1.61 mm and 4.89 ± 1.94 mm) than in normal subjects (5.24 ± 1.02 mm and 3.39 ± 0.80 mm, P < 0.0001, respectively). Conclusions: Patients with CIDP could be distinguished from controls on 3D SHINKEI. Key points: • 3D SHINKEI could visualize brachial plexus with high spatial resolution. • CIDP patients showed increased SNR, CR, and the size of brachial plexus. • 3D SHINKEI could discriminate CIDP patients from normal subjects.
AB - Objective: To evaluate the usefulness of 3D nerve-sheath signal increased with inked rest-tissue rapid acquisition of relaxation enhancement imaging (SHINKEI) in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods: This institutional review board-approved retrospective study included 14 CIDP patients and nine normal subjects. The signal-to-noise ratio (SNR), contrast ratio (CR), and the size of the cervical ganglions and roots were measured by two raters. Results: The SNRs of the ganglions and roots were larger in patients with CIDP (9.55 ± 3.87 and 9.81 ± 3.64) than in normal subjects (7.21 ± 2.42 and 5.70 ± 2.14, P < 0.0001, respectively). The CRs of the ganglions and roots were larger in patients with CIDP (0.77 ± 0.08 and 0.68 ± 0.12) than in normal subjects (0.72 ± 0.07 and 0.53 ± 0.11, P < 0.0001, respectively). The sizes of the ganglions and the roots were larger in patients with CIDP (6.44 ± 1.61 mm and 4.89 ± 1.94 mm) than in normal subjects (5.24 ± 1.02 mm and 3.39 ± 0.80 mm, P < 0.0001, respectively). Conclusions: Patients with CIDP could be distinguished from controls on 3D SHINKEI. Key points: • 3D SHINKEI could visualize brachial plexus with high spatial resolution. • CIDP patients showed increased SNR, CR, and the size of brachial plexus. • 3D SHINKEI could discriminate CIDP patients from normal subjects.
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U2 - 10.1007/s00330-016-4406-3
DO - 10.1007/s00330-016-4406-3
M3 - Article
C2 - 27208993
AN - SCOPUS:84971622017
SN - 0938-7994
VL - 27
SP - 447
EP - 453
JO - European Radiology
JF - European Radiology
IS - 2
ER -