Parkinson’s disease is said to be the excess output of basal ganglia (inhibitory system) which comes from the lack of dopamine by the degeneration of substantia nigra in the midbrain, and DBS (Deep Brain Stimulation) to the subthalamic nucleus is applied as the symptomatic treatment. This paper investigates the validation the effect of the DBS using the motion analysis of the pronation and supination of forearms. It needed the feature selection that reflects the change of the DBS on/off states and could evaluate the DBS effect quantitatively. The feature of the rotation angle had been found to be one of the suitable features which dynamically indicates a part of the motor function by investigating the change of the feature while DBS status was changed as off, on, and off again.
|Journal||Transactions of Japanese Society for Medical and Biological Engineering|
|Publication status||Published - Aug 17 2014|
All Science Journal Classification (ASJC) codes
- Biomedical Engineering