Evaluation of diffusivity in the anterior lobe of the pituitary gland: 3D turbo field echo with diffusion-sensitized driven-equilibrium preparation

Akio Hiwatashi, T. Yoshiura, O. Togao, K. Yamashita, K. Kikuchi, K. Kobayashi, M. Ohga, S. Sonoda, H. Honda, M. Obara

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE: 3D turbo field echo with diffusion-sensitized driven-equilibrium preparation is a non-echo-planar technique for DWI, which enables high-resolution DWI without field inhomogeneity-related image distortion. The purpose of this study was to evaluate the feasibility of diffusion-sensitized driven-equilibrium turbo field echo in evaluating diffusivity in the normal pituitary gland. MATERIALS AND METHODS: First, validation of diffusion-sensitized driven-equilibrium turbo field echo was attempted by comparing it with echo-planar DWI. Five healthy volunteers were imaged by using diffusion-sensitized driven-equilibrium turbo field echo and echoplanar DWI. The imaging voxel size was 1.5 x 1.5 x 1.5 mm3 for diffusion-sensitized driven-equilibrium turbo field echo and 1.5 x 1.9 x 3.0 mm3 for echo-planar DWI. ADCs measured by the 2 methods in 15 regions of interests (6 in gray matter and 9 in white matter) were compared by using the Pearson correlation coefficient. The ADC in the pituitary anterior lobe was then measured in 10 volunteers by using diffusion-sensitized driven-equilibrium turbo field echo, and the results were compared with those in the pons and vermis by using a paired t test. RESULTS: The ADCs from the 2 methods showed a strong correlation (r = 0.79; P < .0001), confirming the accuracy of the ADC measurement with the diffusion-sensitized driven-equilibrium sequence. The ADCs in the normal pituitary gland were 1.37 ± 0.13 x 10-3 mm 2/s, which were significantly higher than those in the pons (1.01 ± 0.24 x 10-3mm2/s) and the vermis (0.89 ± 0.25 x 10-3 mm2/s, P < .01). CONCLUSIONS: We demonstrated that diffusion-sensitized driven-equilibrium turbo field echo is feasible in assessing ADC in the pituitary gland.

Original languageEnglish
Pages (from-to)95-98
Number of pages4
JournalAmerican Journal of Neuroradiology
Volume35
Issue number1
DOIs
Publication statusPublished - Jan 2014

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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