Evaluation of pluripotency in human intenstinal cells by microfluidic-based single cell deformability analysis

Miyu Terada, Sachiko Ide, Toyohiro Naito, Michiya Matsusaki, Noritada Kaji

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, we have developed a microfluidic device that can analyze the pluripotency of cells by measuring the cell deformability based on ionic current sensing at a single cell level. We successfully identified human colon cancer cells (HT29) with high and low pluripotency based on the deformability information and the result was confirmed by a biochemical assay, Aldehyde Dehydrogenase (ALDH) assay, which is an important biomarker of the pluripotency.

Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1049-1050
Number of pages2
ISBN (Electronic)9781733419017
Publication statusPublished - 2020
Event24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
Duration: Oct 4 2020Oct 9 2020

Publication series

NameMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
CityVirtual, Online
Period10/4/2010/9/20

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering
  • Chemistry(all)
  • Control and Systems Engineering

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