Evaluation of protein function on structurally controlled stereocomplex thin films

Yuya Nagasaka, Hisao Matsuno, Kimio Kurita, Takeshi Serizawa

Research output: Contribution to conferencePaperpeer-review

Abstract

Isotactic and syndiotactic poly(methyl methacrylate)s (PMMAs) form double-stranded helical stereocomplexes with a respective length ratio of 1:2 based on van der Waals interactions in organic solvents. Bioactivities of stereocomplex surfaces are significant for determining the potential for biomedical applications. We prepared PMMA stereocomplex films by a layer-by-layer assembly method, and observed antigen-antibody interactions and enzyme reactions on film surfaces. Effects of film surface structures on antigen-antibody interactions and enzyme reactions were investigated. As a result, it was found that protein activities on stereocomplex films were higher than those on PMMA homogeneous films.

Original languageEnglish
Pages4274-4275
Number of pages2
Publication statusPublished - Dec 1 2006
Externally publishedYes
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: Sep 20 2006Sep 22 2006

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
Country/TerritoryJapan
CityToyama
Period9/20/069/22/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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