Evaluation of protein function on structurally controlled stereocomplex thin films

Yuya Nagasaka, Hisao Matsuno, Kimio Kurita, Takeshi Serizawa

Research output: Contribution to conferencePaper

Abstract

Isotactic and syndiotactic poly(methyl methacrylate)s (PMMAs) form double-stranded helical stereocomplexes with a respective length ratio of 1:2 based on van der Waals interactions in organic solvents. Bioactivities of stereocomplex surfaces are significant for determining the potential for biomedical applications. We prepared PMMA stereocomplex films by a layer-by-layer assembly method, and observed antigen-antibody interactions and enzyme reactions on film surfaces. Effects of film surface structures on antigen-antibody interactions and enzyme reactions were investigated. As a result, it was found that protein activities on stereocomplex films were higher than those on PMMA homogeneous films.

Original languageEnglish
Pages4274-4275
Number of pages2
Publication statusPublished - Dec 1 2006
Externally publishedYes
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: Sep 20 2006Sep 22 2006

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period9/20/069/22/06

Fingerprint

Proteins
Thin films
Antigens
Antibodies
Enzymes
Bioactivity
Polymethyl methacrylates
Surface structure
Organic solvents

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Nagasaka, Y., Matsuno, H., Kurita, K., & Serizawa, T. (2006). Evaluation of protein function on structurally controlled stereocomplex thin films. 4274-4275. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.

Evaluation of protein function on structurally controlled stereocomplex thin films. / Nagasaka, Yuya; Matsuno, Hisao; Kurita, Kimio; Serizawa, Takeshi.

2006. 4274-4275 Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.

Research output: Contribution to conferencePaper

Nagasaka, Y, Matsuno, H, Kurita, K & Serizawa, T 2006, 'Evaluation of protein function on structurally controlled stereocomplex thin films', Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan, 9/20/06 - 9/22/06 pp. 4274-4275.
Nagasaka Y, Matsuno H, Kurita K, Serizawa T. Evaluation of protein function on structurally controlled stereocomplex thin films. 2006. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.
Nagasaka, Yuya ; Matsuno, Hisao ; Kurita, Kimio ; Serizawa, Takeshi. / Evaluation of protein function on structurally controlled stereocomplex thin films. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.2 p.
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