Evaluation of techniques to prevent colorectal anastomotic leakage

Tetsuo Ikeda, Ryuichi Kumashiro, Eiji Oki, Kenji Taketani, Koji Ando, Shinichi Aishima, Tomohiko Akahoshi, Masaru Morita, Yoshihiko Maehara

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background Anastomotic leakage is a major complication after anterior resection for rectal cancer. The double-stapling technique (DST) is the main method for creating a colorectal anastomosis. However, the rate of anastomotic leakage after DST remains high, and the technical risk factors have not been well established. Materials and methods Five methods of colorectal anastomosis were performed on the porcine rectum and colon: single-stapled double-purse-string (SSDP), DST, side-to-side with a linear stapler (SS-L), side-to-side with a circular stapler (SS-C), and SS-C with hand-sewn reinforcement (n = 6 for each method). In each group, burst pressures were tested, paying special attention to the locations of the first disruptions. The anastomosis line, including staples, was embedded in polyester resin, and polished sections were examined histologically. Results Burst pressures were significantly higher in the SS-L and SS-C than those in the SSDP and DST groups (P < 0.001) and were higher in the SS-C with hand-sewn reinforcement than those in the SS-L and SS-C groups (P < 0.001). Remarkably, in the SSDP, DST, and SS-C groups, the first disruptions occurred on the staple line created by the circular stapler. Conclusions The experimentally strongest colorectal anastomosis created with instruments currently in use was a SS-C. This anastomosis does not overlap staple lines and does not require a purse-string suture. Hand-sewn reinforcement was effective in increasing the anastomotic strength.

Original languageEnglish
Pages (from-to)450-457
Number of pages8
JournalJournal of Surgical Research
Volume194
Issue number2
DOIs
Publication statusPublished - Apr 1 2015

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Anastomotic Leak
Hand
Pressure
Polyesters
Rectal Neoplasms
Rectum
Sutures
Colon
Swine

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Evaluation of techniques to prevent colorectal anastomotic leakage. / Ikeda, Tetsuo; Kumashiro, Ryuichi; Oki, Eiji; Taketani, Kenji; Ando, Koji; Aishima, Shinichi; Akahoshi, Tomohiko; Morita, Masaru; Maehara, Yoshihiko.

In: Journal of Surgical Research, Vol. 194, No. 2, 01.04.2015, p. 450-457.

Research output: Contribution to journalArticle

Ikeda, T, Kumashiro, R, Oki, E, Taketani, K, Ando, K, Aishima, S, Akahoshi, T, Morita, M & Maehara, Y 2015, 'Evaluation of techniques to prevent colorectal anastomotic leakage', Journal of Surgical Research, vol. 194, no. 2, pp. 450-457. https://doi.org/10.1016/j.jss.2014.11.045
Ikeda, Tetsuo ; Kumashiro, Ryuichi ; Oki, Eiji ; Taketani, Kenji ; Ando, Koji ; Aishima, Shinichi ; Akahoshi, Tomohiko ; Morita, Masaru ; Maehara, Yoshihiko. / Evaluation of techniques to prevent colorectal anastomotic leakage. In: Journal of Surgical Research. 2015 ; Vol. 194, No. 2. pp. 450-457.
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