Evidence that endogenous gamma interferon is produced early in Listeria monocytogenes infection

A. Nakane, A. Numata, M. Asano, M. Kohanawa, Y. Chen, T. Minagawa

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39 Citations (Scopus)

Abstract

It has been presumed that gamma interferon (IFN-γ), which plays an essential role in antilisterial resistance, is produced late in Listeria monocytogenes infection. In the present study, however, IFN-γ was detected in the bloodstreams and spleens of mice from days 1 to 4 of L. monocytogenes infection by both a double-sandwich enzyme-linked immunosorbent assay and in immunohistochemical technique, suggesting that endogenous IFN-γ is produced early but not late in L. monocytogenes infection.

Original languageEnglish
Pages (from-to)2386-2388
Number of pages3
JournalInfection and Immunity
Volume58
Issue number7
Publication statusPublished - 1990
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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