It has been presumed that gamma interferon (IFN-γ), which plays an essential role in antilisterial resistance, is produced late in Listeria monocytogenes infection. In the present study, however, IFN-γ was detected in the bloodstreams and spleens of mice from days 1 to 4 of L. monocytogenes infection by both a double-sandwich enzyme-linked immunosorbent assay and in immunohistochemical technique, suggesting that endogenous IFN-γ is produced early but not late in L. monocytogenes infection.
|Number of pages||3|
|Journal||Infection and Immunity|
|Publication status||Published - 1990|
All Science Journal Classification (ASJC) codes
- Infectious Diseases