Evolution of a symptomatic diffuse developmental venous anomaly with progressive cerebral atrophy in an atypical case of Sturge-Weber syndrome

Koyo Ohno, Yoshiaki Saito, Masami Togawa, Yuki Shinohara, Takamichi Ito, Hidenori Sugano, Shinji Itamura, Yoko Nishimura, Akiko Tamasaki, Yoshihiro Maegaki

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 2-year-old boy had glaucoma, bilateral facial haemangioma and widespread blue nevi on the trunk and extremities since birth. Dilated medullary veins were detected in the left cerebral periventricular white matter on magnetic resonance imaging (MRI). Macrocephaly and delayed psychomotor development were observed during late infancy, and susceptibility-weighted angiography revealed an extensive developmental venous anomaly with multiple caput medusae throughout bilateral hemispheres, accompanied by periventricular hyperintense alterations on MRI and progressive diffuse atrophy of the cerebral mantle with left-sided predominance. Hypoperfusion in the left cerebral and cerebellar hemisphere was also uncovered. No meningeal haemangioma was observed. This patient may represent a novel subgroup of phakomatosis cases that can be regarded as a variant of Sturge-Weber syndrome.

Original languageEnglish
Pages (from-to)817-821
Number of pages5
JournalBrain and Development
Volume37
Issue number8
DOIs
Publication statusPublished - Sep 1 2015
Externally publishedYes

Fingerprint

Sturge-Weber Syndrome
Hemangioma
Atrophy
Blue Nevus
Magnetic Resonance Imaging
Megalencephaly
Neurocutaneous Syndromes
Cerebrum
Glaucoma
Veins
Angiography
Extremities
Parturition
White Matter

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology

Cite this

Evolution of a symptomatic diffuse developmental venous anomaly with progressive cerebral atrophy in an atypical case of Sturge-Weber syndrome. / Ohno, Koyo; Saito, Yoshiaki; Togawa, Masami; Shinohara, Yuki; Ito, Takamichi; Sugano, Hidenori; Itamura, Shinji; Nishimura, Yoko; Tamasaki, Akiko; Maegaki, Yoshihiro.

In: Brain and Development, Vol. 37, No. 8, 01.09.2015, p. 817-821.

Research output: Contribution to journalArticle

Ohno, K, Saito, Y, Togawa, M, Shinohara, Y, Ito, T, Sugano, H, Itamura, S, Nishimura, Y, Tamasaki, A & Maegaki, Y 2015, 'Evolution of a symptomatic diffuse developmental venous anomaly with progressive cerebral atrophy in an atypical case of Sturge-Weber syndrome', Brain and Development, vol. 37, no. 8, pp. 817-821. https://doi.org/10.1016/j.braindev.2014.12.003
Ohno, Koyo ; Saito, Yoshiaki ; Togawa, Masami ; Shinohara, Yuki ; Ito, Takamichi ; Sugano, Hidenori ; Itamura, Shinji ; Nishimura, Yoko ; Tamasaki, Akiko ; Maegaki, Yoshihiro. / Evolution of a symptomatic diffuse developmental venous anomaly with progressive cerebral atrophy in an atypical case of Sturge-Weber syndrome. In: Brain and Development. 2015 ; Vol. 37, No. 8. pp. 817-821.
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