Evolution of prokaryotic gene order: Genome rearrangements in closely related species

Mikita Suyama, Peer Bork

Research output: Contribution to journalShort surveypeer-review

118 Citations (Scopus)

Abstract

Conservation of gene order in prokaryotes has become important in predicting protein function because, over the evolutionary timescale, genomes are shuffled so that local gene-order conservation reflects the functional constraints within the protein. Here, we compare closely related genomes to identify the rate with which gene order is disrupted and to infer the genes involved in the genome rearrangement.

Original languageEnglish
Pages (from-to)10-13
Number of pages4
JournalTrends in Genetics
Volume17
Issue number1
DOIs
Publication statusPublished - Jan 1 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics

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