Abstract
To infer the genealogical relationships of α-amylase electromorphs of Drosophila melanogaster, we determined the nucleotide sequences of a collection of electromorphs sampled throughout the world. On average there were 1.0 amino acid substitutions between identical electromorphs and 3.9 between different electromorphs, respectively. We found that the evolution of AMY1 through AMY6 electromorphs occurred by sequential accumulation of single amino acid substitutions each causing one charge difference. The nucleotide diversities at synonymous sites within Amy1, Amy2, Amy3, Amy4 and Amy6 were 0.0321, 0.0000, 0.0355, 0.0059 and 0.0030, respectively. We also obtained evidence of genetic exchanges, such as intrachromosomal recombination, interchromosomal recombination or gene conversion, between the two duplicated Amy genes as well as among the alleles.
| Original language | English |
|---|---|
| Pages (from-to) | 237-244 |
| Number of pages | 8 |
| Journal | Genetics |
| Volume | 141 |
| Issue number | 1 |
| Publication status | Published - Jan 1 1995 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Genetics
Cite this
Evolutionary relationships and sequence variation of α-amylase variants encoded by duplicated genes in the Amy locus of Drosophila melanogaster. / Inomata, N.; Shibata, Hiroki; Okuyama, E.; Yamazaki, T.
In: Genetics, Vol. 141, No. 1, 01.01.1995, p. 237-244.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evolutionary relationships and sequence variation of α-amylase variants encoded by duplicated genes in the Amy locus of Drosophila melanogaster
AU - Inomata, N.
AU - Shibata, Hiroki
AU - Okuyama, E.
AU - Yamazaki, T.
PY - 1995/1/1
Y1 - 1995/1/1
N2 - To infer the genealogical relationships of α-amylase electromorphs of Drosophila melanogaster, we determined the nucleotide sequences of a collection of electromorphs sampled throughout the world. On average there were 1.0 amino acid substitutions between identical electromorphs and 3.9 between different electromorphs, respectively. We found that the evolution of AMY1 through AMY6 electromorphs occurred by sequential accumulation of single amino acid substitutions each causing one charge difference. The nucleotide diversities at synonymous sites within Amy1, Amy2, Amy3, Amy4 and Amy6 were 0.0321, 0.0000, 0.0355, 0.0059 and 0.0030, respectively. We also obtained evidence of genetic exchanges, such as intrachromosomal recombination, interchromosomal recombination or gene conversion, between the two duplicated Amy genes as well as among the alleles.
AB - To infer the genealogical relationships of α-amylase electromorphs of Drosophila melanogaster, we determined the nucleotide sequences of a collection of electromorphs sampled throughout the world. On average there were 1.0 amino acid substitutions between identical electromorphs and 3.9 between different electromorphs, respectively. We found that the evolution of AMY1 through AMY6 electromorphs occurred by sequential accumulation of single amino acid substitutions each causing one charge difference. The nucleotide diversities at synonymous sites within Amy1, Amy2, Amy3, Amy4 and Amy6 were 0.0321, 0.0000, 0.0355, 0.0059 and 0.0030, respectively. We also obtained evidence of genetic exchanges, such as intrachromosomal recombination, interchromosomal recombination or gene conversion, between the two duplicated Amy genes as well as among the alleles.
UR - http://www.scopus.com/inward/record.url?scp=0029152118&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029152118&partnerID=8YFLogxK
M3 - Article
VL - 141
SP - 237
EP - 244
JO - Genetics
JF - Genetics
SN - 0016-6731
IS - 1
ER -