Expeditious tandem-metathesis route to the AB-ring fragment of ciguatoxin

Hiroki Oguri, Shin ya Sasaki, Tohru Oishi, Masahiro Hirama

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

The AB-ring fragment of ciguatoxin was synthesized in ten steps from tri-O-benzyl-D-glucal based on a highly diastereoselective ring-closing metathesis and subsequent cross metathesis.

Original languageEnglish
Pages (from-to)5405-5408
Number of pages4
JournalTetrahedron Letters
Volume40
Issue number29
DOIs
Publication statusPublished - Jul 16 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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