Experimental lens-induced granulomatous endophthalmitis in guinea pigs

S. I. Ishimoto, H. Sanui, T. Ishibashi, H. Inomata

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We have produced an experimental lens-induced granulomatous endophthalmitis (ELGE) after one intravitreous injection with porcine serum albumin (PSA) and lens disruption in guinea pigs that had previously treated with only one systemic sensitization with PSA in complete Freund's adjuvant. This method is a new and easier way to produce ELGE. Histopathologically, the present animal model showed a typical zonal granulomatous inflammation around the ruptured lens. These findings resemble those in the patients of lens-induced endophthalmitis.

Original languageEnglish
Title of host publicationOcular immunology today
Subtitle of host publicationproceedings of the 5th International Symposium on the Immunology and Immunopathology of the Eye. ICS918
EditorsM. Usui, S. Ohno, K. Aoki, M. Usui, S. Ohno, K. Aoki
PublisherElsevier Science Publishers B.V.
Pages167-170
Number of pages4
ISBN (Print)0444813675
Publication statusPublished - Jan 1 1990
EventThe 5th International Symposium on the Immunology and Immunopathology of the Eye -
Duration: Mar 13 1990Mar 15 1990

Publication series

NameOcular immunology today: proceedings of the 5th International Symposium on the Immunology and Immunopathology of the Eye. ICS918

Other

OtherThe 5th International Symposium on the Immunology and Immunopathology of the Eye
Period3/13/903/15/90

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All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Ishimoto, S. I., Sanui, H., Ishibashi, T., & Inomata, H. (1990). Experimental lens-induced granulomatous endophthalmitis in guinea pigs. In M. Usui, S. Ohno, K. Aoki, M. Usui, S. Ohno, & K. Aoki (Eds.), Ocular immunology today: proceedings of the 5th International Symposium on the Immunology and Immunopathology of the Eye. ICS918 (pp. 167-170). (Ocular immunology today: proceedings of the 5th International Symposium on the Immunology and Immunopathology of the Eye. ICS918). Elsevier Science Publishers B.V..