Experimental macular edema of commotio retinae

Preliminary report

T. Kohno, Tatsuro Ishibashi, H. Inomata, H. Ikui, Y. Taniguchi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Experimental macular edema of commotio retinae was studied in rhesus monkeys. Clinically, opacification of the retina in these experimental animals closely resembled commotio retinae of man. No pigment epithelial damage was detected by ophthalmoscopy and fluorescein angiography showed no leakage from the retinal and choroidal circulations in the macular region. Histologically, macular swelling was apparent and was due primarily to changes of the outer plexiform layer. In this layer, swelling of the axons of the photoreceptor cells was prominent. Intracellular edema was also detected in the Muller cell processes in the inner retina and in the pigment epithelial cells. Prominent changes also occurred in the inner and outer segments of the photoreceptor cells. Disruption of the blood-retinal barrier was not found using horseradish peroxidase as a tracer. We concluded that retinal opacification was due to disarrangement and intracellular edema of the cellular elements of the retina, perhaps a direct result of movement of intracellular fluid in response to mechanical injury.

Original languageEnglish
Pages (from-to)149-156
Number of pages8
JournalJapanese Journal of Ophthalmology
Volume27
Issue number1
Publication statusPublished - Jun 2 1983

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Macular Edema
Retina
Photoreceptor Cells
Edema
Intracellular Fluid
Blood-Retinal Barrier
Ependymoglial Cells
Ophthalmoscopy
Fluorescein Angiography
Horseradish Peroxidase
Macaca mulatta
Axons
Epithelial Cells
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Kohno, T., Ishibashi, T., Inomata, H., Ikui, H., & Taniguchi, Y. (1983). Experimental macular edema of commotio retinae: Preliminary report. Japanese Journal of Ophthalmology, 27(1), 149-156.

Experimental macular edema of commotio retinae : Preliminary report. / Kohno, T.; Ishibashi, Tatsuro; Inomata, H.; Ikui, H.; Taniguchi, Y.

In: Japanese Journal of Ophthalmology, Vol. 27, No. 1, 02.06.1983, p. 149-156.

Research output: Contribution to journalArticle

Kohno, T, Ishibashi, T, Inomata, H, Ikui, H & Taniguchi, Y 1983, 'Experimental macular edema of commotio retinae: Preliminary report', Japanese Journal of Ophthalmology, vol. 27, no. 1, pp. 149-156.
Kohno, T. ; Ishibashi, Tatsuro ; Inomata, H. ; Ikui, H. ; Taniguchi, Y. / Experimental macular edema of commotio retinae : Preliminary report. In: Japanese Journal of Ophthalmology. 1983 ; Vol. 27, No. 1. pp. 149-156.
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