Expression of a Vibrio parahaemolyticus toxin in Escherichia coli results in chromosomal DNA degradation

Jing Zhang, Saki Taniguchi, Hironori Ito, Kazuhiro Iiyama, Madoka Hino, Tsutomu Katayama, Makoto Kimura

Research output: Contribution to journalArticle

Abstract

A toxin-antitoxin system, vp1842/vp1843, locates within a superintegron on the Vibrio parahaemolyticus genome chromosome I whose toxin gene vp1843 encodes a DNA nicking endonuclease. We found that the vp1843 expression in Escherichia coli cells strongly induced chromosomal DNA degradation. On the basis of these observations, we discuss a possible physiological role of vp1842/vp1843 in V. parahaemolyticus.

Original languageEnglish
Pages (from-to)1937-1940
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume81
Issue number10
DOIs
Publication statusPublished - Jan 1 2017

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Vibrio parahaemolyticus
Escherichia coli
Genes
Antitoxins
Degradation
Endonucleases
Deoxyribonuclease I
DNA
Chromosomes
Genome
scorpion toxin I''

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

Expression of a Vibrio parahaemolyticus toxin in Escherichia coli results in chromosomal DNA degradation. / Zhang, Jing; Taniguchi, Saki; Ito, Hironori; Iiyama, Kazuhiro; Hino, Madoka; Katayama, Tsutomu; Kimura, Makoto.

In: Bioscience, Biotechnology and Biochemistry, Vol. 81, No. 10, 01.01.2017, p. 1937-1940.

Research output: Contribution to journalArticle

Zhang, Jing ; Taniguchi, Saki ; Ito, Hironori ; Iiyama, Kazuhiro ; Hino, Madoka ; Katayama, Tsutomu ; Kimura, Makoto. / Expression of a Vibrio parahaemolyticus toxin in Escherichia coli results in chromosomal DNA degradation. In: Bioscience, Biotechnology and Biochemistry. 2017 ; Vol. 81, No. 10. pp. 1937-1940.
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