Extended linkage disequilibrium in noncoding regions in a conifer, Cryptomeria Japonica

Etsuko Moritsuka, Yosuke Hisataka, Miho Tamura, Kentaro Uchiyama, Atsushi Watanabe, Yoshihiko Tsumura, Hidenori Tachida

Research output: Contribution to journalComment/debate

28 Citations (Scopus)

Abstract

We measured linkage disequilibrium in mostly noncoding regions of Cryptomeria japonica, a conifer belonging to Cupressaceae. Linkage disequilibrium was extensive and did not decay even at a distance of 100 kb. The average estimate of the population recombination rate per base pair was 1.55×10 -5 and was <1/70 of that in the coding regions. We discuss the impact of low recombination rates in a large part of the genome on association studies.

Original languageEnglish
Pages (from-to)1145-1148
Number of pages4
JournalGenetics
Volume190
Issue number3
DOIs
Publication statusPublished - Mar 2012

All Science Journal Classification (ASJC) codes

  • Genetics

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    Moritsuka, E., Hisataka, Y., Tamura, M., Uchiyama, K., Watanabe, A., Tsumura, Y., & Tachida, H. (2012). Extended linkage disequilibrium in noncoding regions in a conifer, Cryptomeria Japonica. Genetics, 190(3), 1145-1148. https://doi.org/10.1534/genetics.111.136697