Extension and measurements on multicomponent phospholipid vesicles by use of dual-beam optical tweezers

Masatoshi Ichikawa, Yoko Shitamichi, Yasuyuki Kimura

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A micrometer-sized giant vesicle is studied by extending from the inside by using dual-beam optical tweezers in order to measure mechanical properties such as bending rigidity and surface tension of the membrane. As a micrometer-sized vesicle is extended, its shape gradually changes from a sphere to a lemon-shape, and discretely the lemon-shape deforms into a shape of a tube beside a sphere or a lemon part. The surface tension and the bending rigidity of the lipid membrane are obtained from the measured force-extension curve. In the one-phase vesicle, it is found that the surface tension is increasing as the charged component increasing, but the bending rigidity remains almost constant. In the phase-separated vesicle, the characteristic deformation different from one in the one-phase vesicle has been observed.

Original languageEnglish
Title of host publication20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
Pages170-175
Number of pages6
DOIs
Publication statusPublished - Dec 1 2009
Event20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science - Nagoya, Japan
Duration: Nov 8 2009Nov 11 2009

Publication series

Name20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science

Other

Other20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
CountryJapan
CityNagoya
Period11/8/0911/11/09

All Science Journal Classification (ASJC) codes

  • Computer Science(all)
  • Control and Systems Engineering
  • Electrical and Electronic Engineering

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    Ichikawa, M., Shitamichi, Y., & Kimura, Y. (2009). Extension and measurements on multicomponent phospholipid vesicles by use of dual-beam optical tweezers. In 20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science (pp. 170-175). [5351928] (20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science). https://doi.org/10.1109/MHS.2009.5351928