Extraction of lactic acid from fermented broth with microporous hollow fiber membranes

Yanping Tong, Makoto Hirata, Hirokazu Takanashi, Tadashi Hano, Fukiko Kubota, Masahiro Goto, Fumiyuki Nakashio, Michiaki Matsumoto

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Non-dispersive solvent extraction of lactic acid based on anion-exchange reaction with tri-n-octylmethylammonium chloride dissolved in oleyl alcohol, the optimum extraction reagents selected for extractive fermentation of lactic acid with Lactobacillus rhamnosus, was attempted in a microporous hollow fiber membrane device. A satisfactory recovery of lactic acid from both aqueous solution and actual fermented broth was accomplished, signifying the great potential of integrating the membrane extraction with fermentation process. A theoretical model which took into account the mass transfer resistances across organic and aqueous films and membrane was developed to analyze and predict the extraction behavior. The model prediction was found to be in good agreement with the experimentally observed results.

Original languageEnglish
Pages (from-to)81-91
Number of pages11
JournalJournal of Membrane Science
Volume143
Issue number1-2
DOIs
Publication statusPublished - May 27 1998

Fingerprint

broths
lactic acid
Lactic acid
hollow
Lactic Acid
fermentation
membranes
Membranes
Fermentation
fibers
Fibers
Lactobacillus rhamnosus
solvent extraction
Solvent extraction
Membrane Potentials
mass transfer
Anions
reagents
Chlorides
Ion exchange

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Materials Science(all)
  • Physical and Theoretical Chemistry
  • Filtration and Separation

Cite this

Extraction of lactic acid from fermented broth with microporous hollow fiber membranes. / Tong, Yanping; Hirata, Makoto; Takanashi, Hirokazu; Hano, Tadashi; Kubota, Fukiko; Goto, Masahiro; Nakashio, Fumiyuki; Matsumoto, Michiaki.

In: Journal of Membrane Science, Vol. 143, No. 1-2, 27.05.1998, p. 81-91.

Research output: Contribution to journalArticle

Tong, Yanping ; Hirata, Makoto ; Takanashi, Hirokazu ; Hano, Tadashi ; Kubota, Fukiko ; Goto, Masahiro ; Nakashio, Fumiyuki ; Matsumoto, Michiaki. / Extraction of lactic acid from fermented broth with microporous hollow fiber membranes. In: Journal of Membrane Science. 1998 ; Vol. 143, No. 1-2. pp. 81-91.
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