Extrapulmonary small cell carcinoma in head and neck

Ryuji Yasumatsu, Torahiko Nakashima, M. Yamauchi, S. Toh, S. Komune

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: The management of extrapulmonary small cell carcinoma has not been standardised to date. This study reviewed the clinical course, management and survival outcomes of patients with extrapulmonary small cell carcinoma in the head and neck region. Methods: Nine patients with extrapulmonary small cell carcinoma in the head and neck were included in this study. Results: Five patients received radical surgery followed by adjuvant chemotherapy or radiotherapy or both. Two other patients were treated with chemotherapy consisting of CPT11 plus cisplatin or CPT11 plus cisplatin plus VP-16 three times. Two other patients received chemoradiotherapy consisting of S-1 or CPT11 plus cisplatin. The median overall survival was 14.5 months, with a three-year survival rate of 23.7 per cent. Conclusions: The prognosis of extrapulmonary small cell carcinoma is generally poor. Further prospective multicentre studies are required for better understanding of disease entities and response to treatment modalities.

Original languageEnglish
Pages (from-to)S83-S85
JournalJournal of Laryngology and Otology
Volume129
Issue numberS2
DOIs
Publication statusPublished - Jan 1 2015

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Small Cell Carcinoma
Neck
Head
Cisplatin
Adjuvant Radiotherapy
Survival
Chemoradiotherapy
Etoposide
Adjuvant Chemotherapy
Multicenter Studies
Survival Rate
Prospective Studies
Drug Therapy

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Extrapulmonary small cell carcinoma in head and neck. / Yasumatsu, Ryuji; Nakashima, Torahiko; Yamauchi, M.; Toh, S.; Komune, S.

In: Journal of Laryngology and Otology, Vol. 129, No. S2, 01.01.2015, p. S83-S85.

Research output: Contribution to journalArticle

Yasumatsu, Ryuji ; Nakashima, Torahiko ; Yamauchi, M. ; Toh, S. ; Komune, S. / Extrapulmonary small cell carcinoma in head and neck. In: Journal of Laryngology and Otology. 2015 ; Vol. 129, No. S2. pp. S83-S85.
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