Abstract
Magnesium substituted low crystalline β‑tricalcium phosphates (LC-β-TCP) is an attractive biomaterials owing to its high initial osteoconductivity and bone regeneration. The present investigation is focused on fabrication of low crystalline β-TCP (LC-β-TCP) and evaluating in vitro dissolution toward to the crystallinity of the LC-β-TCP. It is suggested that the crystallinity of biocompatible ceramics greatly affect into their biocompatibility. The novelty of the work is the preparation of the LC-β-TCP without any calcium carbonate/phosphate complex, which is commonly in use. LC-β-TCP was fabricated from MgHPO 4 ·3H 2 O (MgP) and CaCl 2 aqueous solution at 200 °C hydrothermal condition. In vitro dissolution evaluations simulated osteoclast condition indicated the release of Mg 2+ and Ca 2+ . It is suggested that LC -β-TCP fabricated by the given method could be useful material for bone regeneration because it has both low crystallinity and suitable Ca 2+ and Mg 2+ releasing and most importantly it does not contain any extended protocol.
| Original language | English |
|---|---|
| Pages (from-to) | 228-231 |
| Number of pages | 4 |
| Journal | Materials Science and Engineering C |
| Volume | 101 |
| DOIs | |
| Publication status | Published - Aug 1 2019 |
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All Science Journal Classification (ASJC) codes
- Materials Science(all)
- Condensed Matter Physics
- Mechanics of Materials
- Mechanical Engineering
Cite this
Fabrication and in vitro dissolution evaluation of low-crystalline β-TCP blocks through aqueous solution mediated phase conversion. / Tripathi, Garima; Ishikawa, Kunio.
In: Materials Science and Engineering C, Vol. 101, 01.08.2019, p. 228-231.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fabrication and in vitro dissolution evaluation of low-crystalline β-TCP blocks through aqueous solution mediated phase conversion
AU - Tripathi, Garima
AU - Ishikawa, Kunio
PY - 2019/8/1
Y1 - 2019/8/1
N2 - Magnesium substituted low crystalline β‑tricalcium phosphates (LC-β-TCP) is an attractive biomaterials owing to its high initial osteoconductivity and bone regeneration. The present investigation is focused on fabrication of low crystalline β-TCP (LC-β-TCP) and evaluating in vitro dissolution toward to the crystallinity of the LC-β-TCP. It is suggested that the crystallinity of biocompatible ceramics greatly affect into their biocompatibility. The novelty of the work is the preparation of the LC-β-TCP without any calcium carbonate/phosphate complex, which is commonly in use. LC-β-TCP was fabricated from MgHPO 4 ·3H 2 O (MgP) and CaCl 2 aqueous solution at 200 °C hydrothermal condition. In vitro dissolution evaluations simulated osteoclast condition indicated the release of Mg 2+ and Ca 2+ . It is suggested that LC -β-TCP fabricated by the given method could be useful material for bone regeneration because it has both low crystallinity and suitable Ca 2+ and Mg 2+ releasing and most importantly it does not contain any extended protocol.
AB - Magnesium substituted low crystalline β‑tricalcium phosphates (LC-β-TCP) is an attractive biomaterials owing to its high initial osteoconductivity and bone regeneration. The present investigation is focused on fabrication of low crystalline β-TCP (LC-β-TCP) and evaluating in vitro dissolution toward to the crystallinity of the LC-β-TCP. It is suggested that the crystallinity of biocompatible ceramics greatly affect into their biocompatibility. The novelty of the work is the preparation of the LC-β-TCP without any calcium carbonate/phosphate complex, which is commonly in use. LC-β-TCP was fabricated from MgHPO 4 ·3H 2 O (MgP) and CaCl 2 aqueous solution at 200 °C hydrothermal condition. In vitro dissolution evaluations simulated osteoclast condition indicated the release of Mg 2+ and Ca 2+ . It is suggested that LC -β-TCP fabricated by the given method could be useful material for bone regeneration because it has both low crystallinity and suitable Ca 2+ and Mg 2+ releasing and most importantly it does not contain any extended protocol.
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UR - http://www.scopus.com/inward/citedby.url?scp=85063689793&partnerID=8YFLogxK
U2 - 10.1016/j.msec.2019.03.106
DO - 10.1016/j.msec.2019.03.106
M3 - Article
C2 - 31029315
AN - SCOPUS:85063689793
VL - 101
SP - 228
EP - 231
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
SN - 0928-4931
ER -