Fabrication of bone cement that fully transforms to carbonate apatite

Arief Cahyanto; Michito Maruta; Kanji Tsuru; Shigeki Matsuya; Kunio Ishikawa

doi:10.4012/dmj.2014-328

Fabrication of bone cement that fully transforms to carbonate apatite

Arief Cahyanto, Michito Maruta, Kanji Tsuru, Shigeki Matsuya, Kunio Ishikawa

Oral Rehabilitation

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35 Citations (Scopus)

Abstract

The objective of this study was to fabricate a type of bone cement that could fully transform to carbonate apatite (CO₃Ap) in physiological conditions. A combination of calcium carbonate (CaCO₃) and dicalcium phosphate anhydrous was chosen as the powder phase and mixed with one of three kinds of sodium phosphate solutions: NaH₂PO₄, Na₂HPO₄, or Na₃PO₄. The cement that fully transformed to CO₃Ap was fabricated using vaterite, instead of calcite, as a CaCO₃ source. Their stability in aqueous solutions was different, regardless of the type of sodium phosphate solution. Rate of transformation to CO₃Ap in descending order was Na₃PO₄>Na₂HPO₄>NaH₂PO₄. Transformation rate could be affected by the pH of solution. Results of this study showed that it was advantageous to use vaterite to fabricate CO₃Ap-forming cement.

Original language	English
Pages (from-to)	394-401
Number of pages	8
Journal	dental materials journal
Volume	34
Issue number	3
DOIs	https://doi.org/10.4012/dmj.2014-328
Publication status	Published - Apr 23 2015

All Science Journal Classification (ASJC) codes

Ceramics and Composites
Dentistry(all)

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abstract = "The objective of this study was to fabricate a type of bone cement that could fully transform to carbonate apatite (CO3Ap) in physiological conditions. A combination of calcium carbonate (CaCO3) and dicalcium phosphate anhydrous was chosen as the powder phase and mixed with one of three kinds of sodium phosphate solutions: NaH2PO4, Na2HPO4, or Na3PO4. The cement that fully transformed to CO3Ap was fabricated using vaterite, instead of calcite, as a CaCO3 source. Their stability in aqueous solutions was different, regardless of the type of sodium phosphate solution. Rate of transformation to CO3Ap in descending order was Na3PO4>Na2HPO4>NaH2PO4. Transformation rate could be affected by the pH of solution. Results of this study showed that it was advantageous to use vaterite to fabricate CO3Ap-forming cement.",

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AU - Cahyanto, Arief

AU - Maruta, Michito

AU - Tsuru, Kanji

AU - Matsuya, Shigeki

AU - Ishikawa, Kunio

PY - 2015/4/23

Y1 - 2015/4/23

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Fabrication of bone cement that fully transforms to carbonate apatite

Abstract

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