Fabrication of carbonate apatite block through a dissolution-precipitation reaction using calcium hydrogen phosphate dihydrate block as a precursor

Kanji Tsuru, Ayami Yoshimoto, Masayuki Kanazawa, Yuki Sugiura, Yasuharu Nakashima, Kunio Ishikawa

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Carbonate apatite (CO3Ap) block, which is a bone replacement used to repair defects, was fabricated through a dissolution-precipitation reaction using a calcium hydrogen phosphate dihydrate (DCPD) block as a precursor. When the DCPD block was immersed in NaHCO3 or Na2CO3 solution at 80 °C, DCPD converted to CO3Ap within 3 days. β-Tricalcium phosphate was formed as an intermediate phase, and it was completely converted to CO3Ap within 2 weeks when the DCPD block was immersed in Na2CO3 solution. Although the crystal structures of the DCPD and CO3Ap blocks were different, the macroscopic structure was maintained during the compositional transformation through the dissolution-precipitation reaction. CO3Ap block fabricated in NaHCO3 or Na2CO3 solution contained 12.9 and 15.8 wt % carbonate, respectively. The diametral tensile strength of the CO3Ap block was 2 MPa, and the porosity was approximately 57% regardless of the carbonate solution. DCPD is a useful precursor for the fabrication of CO3Ap block.

Original languageEnglish
Article number374
JournalMaterials
Volume10
Issue number4
DOIs
Publication statusPublished - Mar 31 2017

Fingerprint

Apatite
Carbonates
Calcium
Dissolution
Phosphates
Fabrication
Hydrogen
Bone
Repair
Tensile strength
Porosity
Crystal structure
Defects
anhydrous dibasic calcium phosphate
carboapatite

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

Cite this

Fabrication of carbonate apatite block through a dissolution-precipitation reaction using calcium hydrogen phosphate dihydrate block as a precursor. / Tsuru, Kanji; Yoshimoto, Ayami; Kanazawa, Masayuki; Sugiura, Yuki; Nakashima, Yasuharu; Ishikawa, Kunio.

In: Materials, Vol. 10, No. 4, 374, 31.03.2017.

Research output: Contribution to journalArticle

@article{cf0162bf772c4478bc99888dd1253777,
title = "Fabrication of carbonate apatite block through a dissolution-precipitation reaction using calcium hydrogen phosphate dihydrate block as a precursor",
abstract = "Carbonate apatite (CO3Ap) block, which is a bone replacement used to repair defects, was fabricated through a dissolution-precipitation reaction using a calcium hydrogen phosphate dihydrate (DCPD) block as a precursor. When the DCPD block was immersed in NaHCO3 or Na2CO3 solution at 80 °C, DCPD converted to CO3Ap within 3 days. β-Tricalcium phosphate was formed as an intermediate phase, and it was completely converted to CO3Ap within 2 weeks when the DCPD block was immersed in Na2CO3 solution. Although the crystal structures of the DCPD and CO3Ap blocks were different, the macroscopic structure was maintained during the compositional transformation through the dissolution-precipitation reaction. CO3Ap block fabricated in NaHCO3 or Na2CO3 solution contained 12.9 and 15.8 wt {\%} carbonate, respectively. The diametral tensile strength of the CO3Ap block was 2 MPa, and the porosity was approximately 57{\%} regardless of the carbonate solution. DCPD is a useful precursor for the fabrication of CO3Ap block.",
author = "Kanji Tsuru and Ayami Yoshimoto and Masayuki Kanazawa and Yuki Sugiura and Yasuharu Nakashima and Kunio Ishikawa",
year = "2017",
month = "3",
day = "31",
doi = "10.3390/ma10040374",
language = "English",
volume = "10",
journal = "Materials",
issn = "1996-1944",
publisher = "MDPI AG",
number = "4",

}

TY - JOUR

T1 - Fabrication of carbonate apatite block through a dissolution-precipitation reaction using calcium hydrogen phosphate dihydrate block as a precursor

AU - Tsuru, Kanji

AU - Yoshimoto, Ayami

AU - Kanazawa, Masayuki

AU - Sugiura, Yuki

AU - Nakashima, Yasuharu

AU - Ishikawa, Kunio

PY - 2017/3/31

Y1 - 2017/3/31

N2 - Carbonate apatite (CO3Ap) block, which is a bone replacement used to repair defects, was fabricated through a dissolution-precipitation reaction using a calcium hydrogen phosphate dihydrate (DCPD) block as a precursor. When the DCPD block was immersed in NaHCO3 or Na2CO3 solution at 80 °C, DCPD converted to CO3Ap within 3 days. β-Tricalcium phosphate was formed as an intermediate phase, and it was completely converted to CO3Ap within 2 weeks when the DCPD block was immersed in Na2CO3 solution. Although the crystal structures of the DCPD and CO3Ap blocks were different, the macroscopic structure was maintained during the compositional transformation through the dissolution-precipitation reaction. CO3Ap block fabricated in NaHCO3 or Na2CO3 solution contained 12.9 and 15.8 wt % carbonate, respectively. The diametral tensile strength of the CO3Ap block was 2 MPa, and the porosity was approximately 57% regardless of the carbonate solution. DCPD is a useful precursor for the fabrication of CO3Ap block.

AB - Carbonate apatite (CO3Ap) block, which is a bone replacement used to repair defects, was fabricated through a dissolution-precipitation reaction using a calcium hydrogen phosphate dihydrate (DCPD) block as a precursor. When the DCPD block was immersed in NaHCO3 or Na2CO3 solution at 80 °C, DCPD converted to CO3Ap within 3 days. β-Tricalcium phosphate was formed as an intermediate phase, and it was completely converted to CO3Ap within 2 weeks when the DCPD block was immersed in Na2CO3 solution. Although the crystal structures of the DCPD and CO3Ap blocks were different, the macroscopic structure was maintained during the compositional transformation through the dissolution-precipitation reaction. CO3Ap block fabricated in NaHCO3 or Na2CO3 solution contained 12.9 and 15.8 wt % carbonate, respectively. The diametral tensile strength of the CO3Ap block was 2 MPa, and the porosity was approximately 57% regardless of the carbonate solution. DCPD is a useful precursor for the fabrication of CO3Ap block.

UR - http://www.scopus.com/inward/record.url?scp=85017461796&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85017461796&partnerID=8YFLogxK

U2 - 10.3390/ma10040374

DO - 10.3390/ma10040374

M3 - Article

VL - 10

JO - Materials

JF - Materials

SN - 1996-1944

IS - 4

M1 - 374

ER -