Elder people tend to be bedridden by accidents accompanied by bone fractures. Therefore, a solution that maintains the quality of life for patients by providing early recovery of wounded or damaged hard tissues supported by high-functional bone substitutes would be ideal. In this chapter, we will describe the successful fabrication of novel bone substitutes that is similar to natural bone from the perspective of inorganic component, crystallinity, and bioresorbability. These properties are essential if natural bones damaged through falls are fully replaced by artificially synthesized bone substitutes. We will also discuss the concept, synthesis route, and the introduction of interconnected pores into the structures of bone substitutes.