TY - JOUR
T1 - Fabrication of low-crystalline carbonate apatite foam bone replacement based on phase transformation of calcite foam
AU - Maruta, Michito
AU - Matsuya, Shigeki
AU - Nakamura, Seiji
AU - Ishikawa, Kunio
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2011
Y1 - 2011
N2 - Carbonate apatite (CO3Ap) foam may be an ideal bone substitute as it is sidelined to cancellous bone with respect to its chemical composition and structure. However, CO3Ap foam fabricated using α-tricalcium phosphate foam showed limited mechanical strength. In the present study, feasibility of the fabrication of calcite which could be a precursor of CO3Ap was studied. Calcite foam was successfully fabricated by the so-called "ceramic foam" method using calcium hydroxide coated polyurethane foam under CO2+O2 atmosphere. Then the calcite foam was immersed in Na2HPO4 aqueous solution for phase transformation based on dissolutionprecipitation reaction. When CaO-free calcite foam was immersed in Na2HPO4 solution, low-crystalline CO3Ap foam with 93-96% porosity and fully interconnected porous structure was fabricated. The compressive strength of the foam was 25.6±6 kPa. In light of these results, we concluded that the properties of the precursor foam were key factors for the fabrication of CO3Ap foams.
AB - Carbonate apatite (CO3Ap) foam may be an ideal bone substitute as it is sidelined to cancellous bone with respect to its chemical composition and structure. However, CO3Ap foam fabricated using α-tricalcium phosphate foam showed limited mechanical strength. In the present study, feasibility of the fabrication of calcite which could be a precursor of CO3Ap was studied. Calcite foam was successfully fabricated by the so-called "ceramic foam" method using calcium hydroxide coated polyurethane foam under CO2+O2 atmosphere. Then the calcite foam was immersed in Na2HPO4 aqueous solution for phase transformation based on dissolutionprecipitation reaction. When CaO-free calcite foam was immersed in Na2HPO4 solution, low-crystalline CO3Ap foam with 93-96% porosity and fully interconnected porous structure was fabricated. The compressive strength of the foam was 25.6±6 kPa. In light of these results, we concluded that the properties of the precursor foam were key factors for the fabrication of CO3Ap foams.
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U2 - 10.4012/dmj.2010-087
DO - 10.4012/dmj.2010-087
M3 - Article
C2 - 21282893
AN - SCOPUS:79951599148
VL - 30
SP - 14
EP - 20
JO - Dental Materials Journal
JF - Dental Materials Journal
SN - 0287-4547
IS - 1
ER -