Fabrication of oriented helical polypeptide brushes on gold

Masazo Niwa, Masa-Aki Morikawa, Nobuyuki Higashi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

An α-helical poly(γ-benzyl-L-glutamate) labeled at its N-terminus with disulfide moieties, PBLG-SS, was synthesized to examine the self-assembling property of helical rods onto a gold surface. Adsorption processes and resultant helical PBLG-SS monolayers on gold were characterized by quartz crystal microbalance measurements and barrier capability toward [Fe(CN)6]3-/4- in aqueous solution. When PBLG-SS was dissolved in CHCl3, a densely packed monolayer was formed on the gold surface and the helical rods aligned in antiparallel manner based on the helix-macrodipole interaction. In contrast, when PBLG-SS was dissolved in DMSO, a loosely packed monolayer was formed and the helix-macrodipole was directed in the same sense. The electric field at the electrode/electrolyte interface was used to affect helix orientation. As a result, predominant chemisorption of PBLG-SS molecule was present on the negative gold electrode. This is suggestive of parallel alignment of helix-macrodipole on the basis of electric field effects.

Original languageEnglish
Pages (from-to)652-658
Number of pages7
JournalKobunshi Ronbunshu
Volume57
Issue number10
DOIs
Publication statusPublished - Jan 1 2000
Externally publishedYes

Fingerprint

Polypeptides
Brushes
Gold
gold
Fabrication
Monolayers
Peptides
electric field
electrode
Electric field effects
Electrodes
Quartz crystal microbalances
Chemisorption
Dimethyl Sulfoxide
Disulfides
electrolyte
Electrolytes
aqueous solution
Electric fields
crystal

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Materials Science (miscellaneous)
  • Environmental Science(all)
  • Polymers and Plastics

Cite this

Fabrication of oriented helical polypeptide brushes on gold. / Niwa, Masazo; Morikawa, Masa-Aki; Higashi, Nobuyuki.

In: Kobunshi Ronbunshu, Vol. 57, No. 10, 01.01.2000, p. 652-658.

Research output: Contribution to journalArticle

Niwa, Masazo ; Morikawa, Masa-Aki ; Higashi, Nobuyuki. / Fabrication of oriented helical polypeptide brushes on gold. In: Kobunshi Ronbunshu. 2000 ; Vol. 57, No. 10. pp. 652-658.
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