Fabrication of solid and hollow carbonate apatite microspheres as bone substitutes using calcite microspheres as a precursor

Kazuhiro Sunouchi, Kanji Tsuru, Michito Maruta, Giichiro Kawachi, Shigeki Matsuya, Yoshihiro Terada, Kunio Ishikawa

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Spherical carbonate apatite (CO 3Ap) microspheres approximately 1 mm in diameter were fabricated by granulation of calcium hydroxide around a core followed by carbonation and phosphatization through dissolution-precipitation reaction. CO 3Ap microspheres with high uniformity could not be achieved without using a core. Solid CO 3Ap microspheres were obtained using a calcite core whereas hollow CO 3Ap microspheres were obtained using a NaCl core. The obtained microsphere was identified as B-type CO 3Ap by Fourier transform infrared analysis and the carbonate content was approximately 7-8 wt% regardless of the type of core used for sample preparation. The mechanical strength of both the solid and hollow CO 3Ap microspheres was sufficient for practical use as a bone substitute.

Original languageEnglish
Pages (from-to)549-557
Number of pages9
Journaldental materials journal
Volume31
Issue number4
DOIs
Publication statusPublished - Aug 13 2012

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Dentistry(all)

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