Poly(octadecyl acrylate)-grafted silica has been developed as a special stationary phase showing molecular-shape recognition in high-performance liquid chromatography. The bonded polymer phase is characterized by the fact that the polymer forms highly-ordered structures similar to a solvated crystalline state on silica and multiple π-π interaction between carbonyl groups in the polymer and aromatic solutes is promoted. This paper shows that the selectivity for DL-amino acids diastereomerized with N-dansyl L-proline can be enhanced by using the polymer stationary phase instead of octadecylated silica (ODS).
|Number of pages||12|
|Journal||Journal of Liquid Chromatography and Related Technologies|
|Publication status||Published - Oct 11 2004|
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Pharmaceutical Science
- Clinical Biochemistry