Facile oxidation of aldehydes and α-keto acids as catalyzed by flavin and thiazolium ion

Seiji Shinkai, Takaharu Yamashita, Yumiko Kusano, Osamu Manabe

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Oxidation of aldehydes and α-keto acids to carboxylic acids ocurrs readily in the presence of a flavin, thiazolium ion, and cationic micelles, the reaction involving trapping by the flavin of the intermediate formed from the substrate-thiazolium adducts through deprotonation or decarboxylation.

Original languageEnglish
Pages (from-to)2543-2546
Number of pages4
JournalTetrahedron Letters
Volume21
Issue number26
DOIs
Publication statusPublished - Jan 1 1980
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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