Facile surface functionalization of polystyrene substrates with biomimetic apatite by utilizing serum proteins

Mineo Hashizume; Atsushi Sakai; Yuri Sakamoto; Hisao Matsuno; Takeshi Serizawa

doi:10.1246/cl.2010.220

Facile surface functionalization of polystyrene substrates with biomimetic apatite by utilizing serum proteins

Mineo Hashizume, Atsushi Sakai, Yuri Sakamoto, Hisao Matsuno, Takeshi Serizawa

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Serum proteins such as human serum albumin and human immunoglobulin G can induce heterogeneous nucleation of hydroxyapatite (HAp) in body fluid conditions, which make it possible for them to act as mediators to deposit HAp on polystyrene (PS) surfaces when they are immobilized on PS surfaces by physical adsorption. The present system for preparation of HAp-coated PS surfaces is simple and conversion of PS chemical structures does not occur, so that it can be applicable to various polymer surfaces having protein adsorption ability.

Original language	English
Pages (from-to)	220-222
Number of pages	3
Journal	Chemistry Letters
Volume	39
Issue number	3
DOIs	https://doi.org/10.1246/cl.2010.220
Publication status	Published - 2010

All Science Journal Classification (ASJC) codes

Chemistry(all)

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10.1246/cl.2010.220

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abstract = "Serum proteins such as human serum albumin and human immunoglobulin G can induce heterogeneous nucleation of hydroxyapatite (HAp) in body fluid conditions, which make it possible for them to act as mediators to deposit HAp on polystyrene (PS) surfaces when they are immobilized on PS surfaces by physical adsorption. The present system for preparation of HAp-coated PS surfaces is simple and conversion of PS chemical structures does not occur, so that it can be applicable to various polymer surfaces having protein adsorption ability.",

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T1 - Facile surface functionalization of polystyrene substrates with biomimetic apatite by utilizing serum proteins

AU - Hashizume, Mineo

AU - Sakai, Atsushi

AU - Sakamoto, Yuri

AU - Matsuno, Hisao

AU - Serizawa, Takeshi

PY - 2010

Y1 - 2010

N2 - Serum proteins such as human serum albumin and human immunoglobulin G can induce heterogeneous nucleation of hydroxyapatite (HAp) in body fluid conditions, which make it possible for them to act as mediators to deposit HAp on polystyrene (PS) surfaces when they are immobilized on PS surfaces by physical adsorption. The present system for preparation of HAp-coated PS surfaces is simple and conversion of PS chemical structures does not occur, so that it can be applicable to various polymer surfaces having protein adsorption ability.

AB - Serum proteins such as human serum albumin and human immunoglobulin G can induce heterogeneous nucleation of hydroxyapatite (HAp) in body fluid conditions, which make it possible for them to act as mediators to deposit HAp on polystyrene (PS) surfaces when they are immobilized on PS surfaces by physical adsorption. The present system for preparation of HAp-coated PS surfaces is simple and conversion of PS chemical structures does not occur, so that it can be applicable to various polymer surfaces having protein adsorption ability.

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Facile surface functionalization of polystyrene substrates with biomimetic apatite by utilizing serum proteins

Abstract

All Science Journal Classification (ASJC) codes

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