Abstract
Aim: Appetite loss has been associated with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Among older people, decreased appetite can result in poor nutrition and subsequent loss of independent living. We examined the factors related to appetite loss in persons with AD and MCI to provide evidence for countermeasures to prevent appetite loss and progression of cognitive impairment. Methods: We included 1238 older adults undergoing outpatient treatment at the Center for Comprehensive Care and Research on Memory Disorders (Medical Center for Dementia) at the National Center for Geriatrics and Gerontology in Obu, Japan. The Council on Nutrition Appetite Questionnaire, an appetite questionnaire for older people, was used to evaluate appetite. Appetite loss in persons diagnosed with AD or MCI was divided into two groups according to the Council on Nutrition Appetite Questionnaire scores, and logistic regression analysis was carried out to identify independent factors associated with appetite loss. The following variables were used to evaluate for covariates: general information, functional evaluation and medications. Results: The AD and MCI groups contained 853 and 385 individuals, respectively. In both groups, depression and difficulty in maintaining attention while eating were significantly associated with poor appetite. Among persons with AD, lower vitality, more comorbidities, non-use of antidementia drugs and use of psychotropic drugs were also significantly associated with poor appetite. Conclusions: The present study recognized possible factors individually associated with appetite loss among persons with AD or MCI. Future studies are required to examine supportive strategies to treat poor appetite in these populations. Geriatr Gerontol Int 2018; 18: 1236–1243.
| Original language | English |
|---|---|
| Pages (from-to) | 1236-1243 |
| Number of pages | 8 |
| Journal | Geriatrics and Gerontology International |
| Volume | 18 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 1 2018 |
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All Science Journal Classification (ASJC) codes
- Health(social science)
- Gerontology
- Geriatrics and Gerontology
Cite this
Factors affecting the appetites of persons with Alzheimer's disease and mild cognitive impairment. / Suma, Shino; Watanabe, Yutaka; Hirano, Hirohiko; Kimura, Ai; Edahiro, Ayako; Awata, Shuichi; Yamashita, Yoshihisa; Matsushita, Kenji; Arai, Hidenori; Sakurai, Takashi.
In: Geriatrics and Gerontology International, Vol. 18, No. 8, 01.08.2018, p. 1236-1243.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Factors affecting the appetites of persons with Alzheimer's disease and mild cognitive impairment
AU - Suma, Shino
AU - Watanabe, Yutaka
AU - Hirano, Hirohiko
AU - Kimura, Ai
AU - Edahiro, Ayako
AU - Awata, Shuichi
AU - Yamashita, Yoshihisa
AU - Matsushita, Kenji
AU - Arai, Hidenori
AU - Sakurai, Takashi
PY - 2018/8/1
Y1 - 2018/8/1
N2 - Aim: Appetite loss has been associated with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Among older people, decreased appetite can result in poor nutrition and subsequent loss of independent living. We examined the factors related to appetite loss in persons with AD and MCI to provide evidence for countermeasures to prevent appetite loss and progression of cognitive impairment. Methods: We included 1238 older adults undergoing outpatient treatment at the Center for Comprehensive Care and Research on Memory Disorders (Medical Center for Dementia) at the National Center for Geriatrics and Gerontology in Obu, Japan. The Council on Nutrition Appetite Questionnaire, an appetite questionnaire for older people, was used to evaluate appetite. Appetite loss in persons diagnosed with AD or MCI was divided into two groups according to the Council on Nutrition Appetite Questionnaire scores, and logistic regression analysis was carried out to identify independent factors associated with appetite loss. The following variables were used to evaluate for covariates: general information, functional evaluation and medications. Results: The AD and MCI groups contained 853 and 385 individuals, respectively. In both groups, depression and difficulty in maintaining attention while eating were significantly associated with poor appetite. Among persons with AD, lower vitality, more comorbidities, non-use of antidementia drugs and use of psychotropic drugs were also significantly associated with poor appetite. Conclusions: The present study recognized possible factors individually associated with appetite loss among persons with AD or MCI. Future studies are required to examine supportive strategies to treat poor appetite in these populations. Geriatr Gerontol Int 2018; 18: 1236–1243.
AB - Aim: Appetite loss has been associated with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Among older people, decreased appetite can result in poor nutrition and subsequent loss of independent living. We examined the factors related to appetite loss in persons with AD and MCI to provide evidence for countermeasures to prevent appetite loss and progression of cognitive impairment. Methods: We included 1238 older adults undergoing outpatient treatment at the Center for Comprehensive Care and Research on Memory Disorders (Medical Center for Dementia) at the National Center for Geriatrics and Gerontology in Obu, Japan. The Council on Nutrition Appetite Questionnaire, an appetite questionnaire for older people, was used to evaluate appetite. Appetite loss in persons diagnosed with AD or MCI was divided into two groups according to the Council on Nutrition Appetite Questionnaire scores, and logistic regression analysis was carried out to identify independent factors associated with appetite loss. The following variables were used to evaluate for covariates: general information, functional evaluation and medications. Results: The AD and MCI groups contained 853 and 385 individuals, respectively. In both groups, depression and difficulty in maintaining attention while eating were significantly associated with poor appetite. Among persons with AD, lower vitality, more comorbidities, non-use of antidementia drugs and use of psychotropic drugs were also significantly associated with poor appetite. Conclusions: The present study recognized possible factors individually associated with appetite loss among persons with AD or MCI. Future studies are required to examine supportive strategies to treat poor appetite in these populations. Geriatr Gerontol Int 2018; 18: 1236–1243.
UR - http://www.scopus.com/inward/record.url?scp=85047666377&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85047666377&partnerID=8YFLogxK
U2 - 10.1111/ggi.13455
DO - 10.1111/ggi.13455
M3 - Article
C2 - 29808955
AN - SCOPUS:85047666377
VL - 18
SP - 1236
EP - 1243
JO - Geriatrics and Gerontology International
JF - Geriatrics and Gerontology International
SN - 1447-0594
IS - 8
ER -