Factors predictive of high-output ileostomy: a retrospective single-center comparative study

Mitsunobu Takeda, Hidekazu Takahashi, Naotsugu Haraguchi, Norikatsu Miyoshi, Taishi Hata, Hirofumi Yamamoto, Chu Matsuda, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: High-output syndrome (HOS) is a complication of ileostomy, which can affect quality of life significantly; however, its exact cause remains unknown. The aim of this study was to establish the frequency, as well as the preoperative and intraoperative factors predictive of HOS. Methods: The subjects of this study were 164 consecutive patients who underwent colorectal cancer surgery with ileostomy construction at our institute between January, 2011 and August, 2018. Thirteen patients with postoperative complications reported as causes of HOS, including intraperitoneal abscess, paralytic ileus, and outlet obstruction, were excluded. We used a logistic regression analysis to identify the factors predictive of HOS. Results: HOS developed in 36 of the 151 patients (23.8%). There were significantly more diabetic patients in the HOS group (P = 0.03), but other patient factors such as age, gender, body mass index, and use of daily laxatives were not significantly different between the groups. The HOS group had significantly more cases of total proctocolectomy (P = 0.04), but other surgical factors such as operative time, and blood transfusion were not significantly different between the two groups. Conclusions: These results indicate that diabetes and total proctocolectomy are preoperative predictors of HOS, allowing for the possibility of early intervention via post-surgical treatment.

Original languageEnglish
Pages (from-to)482-487
Number of pages6
JournalSurgery today
Volume49
Issue number6
DOIs
Publication statusPublished - Jun 1 2019
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery

Fingerprint Dive into the research topics of 'Factors predictive of high-output ileostomy: a retrospective single-center comparative study'. Together they form a unique fingerprint.

  • Cite this

    Takeda, M., Takahashi, H., Haraguchi, N., Miyoshi, N., Hata, T., Yamamoto, H., Matsuda, C., Mizushima, T., Doki, Y., & Mori, M. (2019). Factors predictive of high-output ileostomy: a retrospective single-center comparative study. Surgery today, 49(6), 482-487. https://doi.org/10.1007/s00595-018-1756-2