Familial erythrophagocytic lymphohistiocytosis: Surface marker analysis using monoclonal antibodies

Eiichi Ishii, Toshiro Hara, Shouichi Ohga, Kohji Ueda, Masahiro Suda, Junji Nakamura, Tadamichi Yanagi, Yoshiro Tsuji

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Surface marker analysis of atypical cells, present at elevated levels in the peripheral blood of a 2‐yr‐old patient with familial erythrophagocytic lymphohistiocytosis (FEL), was performed with monoclonal antibodies. The atypical cells expressed T11, T8, Ia and LeuM2 antigens, markers of suppressor/cytotoxic T lymphocyte and monocyte. The monoclonal antibody‐defined surface markers were thus distinguishable from those of other lymphoproliferative disorders clinically resembling FEL.

Original languageEnglish
Pages (from-to)63-66
Number of pages4
JournalEuropean Journal of Haematology
Volume38
Issue number1
DOIs
Publication statusPublished - Jan 1987

All Science Journal Classification (ASJC) codes

  • Hematology

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