Familial erythrophagocytic lymphohistiocytosis: Surface marker analysis using monoclonal antibodies

Eiichi Ishii, Toshiro Hara, Shoichi Ohga, Kohji Ueda, Masahiro Suda, Junji Nakamura, Tadamichi Yanagi, Yoshiro Tsuji

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Surface marker analysis of atypical cells, present at elevated levels in the peripheral blood of a 2‐yr‐old patient with familial erythrophagocytic lymphohistiocytosis (FEL), was performed with monoclonal antibodies. The atypical cells expressed T11, T8, Ia and LeuM2 antigens, markers of suppressor/cytotoxic T lymphocyte and monocyte. The monoclonal antibody‐defined surface markers were thus distinguishable from those of other lymphoproliferative disorders clinically resembling FEL.

Original languageEnglish
Pages (from-to)63-66
Number of pages4
JournalEuropean Journal of Haematology
Volume38
Issue number1
DOIs
Publication statusPublished - Jan 1 1987

Fingerprint

Hemophagocytic Lymphohistiocytosis
Monoclonal Antibodies
Lymphoproliferative Disorders
Histocompatibility Antigens Class II
Cytotoxic T-Lymphocytes
Monocytes

All Science Journal Classification (ASJC) codes

  • Hematology

Cite this

Familial erythrophagocytic lymphohistiocytosis : Surface marker analysis using monoclonal antibodies. / Ishii, Eiichi; Hara, Toshiro; Ohga, Shoichi; Ueda, Kohji; Suda, Masahiro; Nakamura, Junji; Yanagi, Tadamichi; Tsuji, Yoshiro.

In: European Journal of Haematology, Vol. 38, No. 1, 01.01.1987, p. 63-66.

Research output: Contribution to journalArticle

Ishii, Eiichi ; Hara, Toshiro ; Ohga, Shoichi ; Ueda, Kohji ; Suda, Masahiro ; Nakamura, Junji ; Yanagi, Tadamichi ; Tsuji, Yoshiro. / Familial erythrophagocytic lymphohistiocytosis : Surface marker analysis using monoclonal antibodies. In: European Journal of Haematology. 1987 ; Vol. 38, No. 1. pp. 63-66.
@article{e28cdfbc908348a6993087a93d944309,
title = "Familial erythrophagocytic lymphohistiocytosis: Surface marker analysis using monoclonal antibodies",
abstract = "Surface marker analysis of atypical cells, present at elevated levels in the peripheral blood of a 2‐yr‐old patient with familial erythrophagocytic lymphohistiocytosis (FEL), was performed with monoclonal antibodies. The atypical cells expressed T11, T8, Ia and LeuM2 antigens, markers of suppressor/cytotoxic T lymphocyte and monocyte. The monoclonal antibody‐defined surface markers were thus distinguishable from those of other lymphoproliferative disorders clinically resembling FEL.",
author = "Eiichi Ishii and Toshiro Hara and Shoichi Ohga and Kohji Ueda and Masahiro Suda and Junji Nakamura and Tadamichi Yanagi and Yoshiro Tsuji",
year = "1987",
month = "1",
day = "1",
doi = "10.1111/j.1600-0609.1987.tb01426.x",
language = "English",
volume = "38",
pages = "63--66",
journal = "European Journal of Haematology",
issn = "0902-4441",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Familial erythrophagocytic lymphohistiocytosis

T2 - Surface marker analysis using monoclonal antibodies

AU - Ishii, Eiichi

AU - Hara, Toshiro

AU - Ohga, Shoichi

AU - Ueda, Kohji

AU - Suda, Masahiro

AU - Nakamura, Junji

AU - Yanagi, Tadamichi

AU - Tsuji, Yoshiro

PY - 1987/1/1

Y1 - 1987/1/1

N2 - Surface marker analysis of atypical cells, present at elevated levels in the peripheral blood of a 2‐yr‐old patient with familial erythrophagocytic lymphohistiocytosis (FEL), was performed with monoclonal antibodies. The atypical cells expressed T11, T8, Ia and LeuM2 antigens, markers of suppressor/cytotoxic T lymphocyte and monocyte. The monoclonal antibody‐defined surface markers were thus distinguishable from those of other lymphoproliferative disorders clinically resembling FEL.

AB - Surface marker analysis of atypical cells, present at elevated levels in the peripheral blood of a 2‐yr‐old patient with familial erythrophagocytic lymphohistiocytosis (FEL), was performed with monoclonal antibodies. The atypical cells expressed T11, T8, Ia and LeuM2 antigens, markers of suppressor/cytotoxic T lymphocyte and monocyte. The monoclonal antibody‐defined surface markers were thus distinguishable from those of other lymphoproliferative disorders clinically resembling FEL.

UR - http://www.scopus.com/inward/record.url?scp=0023069566&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023069566&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0609.1987.tb01426.x

DO - 10.1111/j.1600-0609.1987.tb01426.x

M3 - Article

C2 - 3582607

AN - SCOPUS:0023069566

VL - 38

SP - 63

EP - 66

JO - European Journal of Haematology

JF - European Journal of Haematology

SN - 0902-4441

IS - 1

ER -