Fear of hypoglycemia and its determinants in insulin-treated patients with type 2 diabetes mellitus

Naoki Sakane; Kazuhiko Kotani; Kokoro Tsuzaki; Masami Nishi; Kaoru Takahashi; Takashi Murata; Kazunori Yamada; Kentaro Okazaki; Katsuyuki Yanagisawa; Kenichi Yamada; Nobuichi Kuribayashi; Yasuo Totsuka; Toru Hiyoshi; Motoji Naka; Masatake Sugimoto; Yuji Aoki; Masako Waki; Miyuki Furuya; Haruko Kitaoka; Mariko Oishi; Ikki Shimizu; Hiroaki Miyaoka; Akira Okada; Toshikazu Yamamoto

doi:10.1111/jdi.12340

Fear of hypoglycemia and its determinants in insulin-treated patients with type 2 diabetes mellitus

Naoki Sakane, Kazuhiko Kotani, Kokoro Tsuzaki, Masami Nishi, Kaoru Takahashi, Takashi Murata, Kazunori Yamada, Kentaro Okazaki, Katsuyuki Yanagisawa, Kenichi Yamada, Nobuichi Kuribayashi, Yasuo Totsuka, Toru Hiyoshi, Motoji Naka, Masatake Sugimoto, Yuji Aoki, Masako Waki, Miyuki Furuya, Haruko Kitaoka, Mariko OishiIkki Shimizu, Hiroaki Miyaoka, Akira Okada, Toshikazu Yamamoto

Research output: Contribution to journal › Article › peer-review

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Abstract

The aim of the present study was to investigate the prevalence of fear of hypoglycemia, in association with severe hypoglycemia and social factors, in insulin-treated patients with type 2 diabetes mellitus. A questionnaire survey on hypoglycemia and patient-physician communication was carried out in 355 patients with insulin-treated type 2 diabetes mellitus patients at 16 hospitals and clinics. A fear of hypoglycemia was reported by 27.7% of patients. A stepwise logistic regression analysis found that severe hypoglycemia during the past 1 year was a significant determinant of fear of hypoglycemia (odds ratio 2.16, 95% confidence interval 1.06-4.41; P = 0.034), and age (odds ratio 1.02, 95% confidence interval 1.00-1.05, P = 0.038) and living alone (odds ratio 1.93, 95% confidence interval 1.00-3.73, P < 0.05) were significantly higher in patients with fear of hypoglycemia than in those without it.

Original language	English
Pages (from-to)	567-570
Number of pages	4
Journal	Journal of Diabetes Investigation
Volume	6
Issue number	5
DOIs	https://doi.org/10.1111/jdi.12340
Publication status	Published - Sept 1 2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

Internal Medicine
Endocrinology, Diabetes and Metabolism

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/jdi.12340

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Sakane, N., Kotani, K., Tsuzaki, K., Nishi, M., Takahashi, K., Murata, T., Yamada, K., Okazaki, K., Yanagisawa, K., Yamada, K., Kuribayashi, N., Totsuka, Y., Hiyoshi, T., Naka, M., Sugimoto, M., Aoki, Y., Waki, M., Furuya, M., Kitaoka, H., ... Yamamoto, T. (2015). Fear of hypoglycemia and its determinants in insulin-treated patients with type 2 diabetes mellitus. Journal of Diabetes Investigation, 6(5), 567-570. https://doi.org/10.1111/jdi.12340

Sakane, N, Kotani, K, Tsuzaki, K, Nishi, M, Takahashi, K, Murata, T, Yamada, K, Okazaki, K, Yanagisawa, K, Yamada, K, Kuribayashi, N, Totsuka, Y, Hiyoshi, T, Naka, M, Sugimoto, M, Aoki, Y, Waki, M, Furuya, M, Kitaoka, H, Oishi, M, Shimizu, I, Miyaoka, H, Okada, A & Yamamoto, T 2015, 'Fear of hypoglycemia and its determinants in insulin-treated patients with type 2 diabetes mellitus', Journal of Diabetes Investigation, vol. 6, no. 5, pp. 567-570. https://doi.org/10.1111/jdi.12340

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abstract = "The aim of the present study was to investigate the prevalence of fear of hypoglycemia, in association with severe hypoglycemia and social factors, in insulin-treated patients with type 2 diabetes mellitus. A questionnaire survey on hypoglycemia and patient-physician communication was carried out in 355 patients with insulin-treated type 2 diabetes mellitus patients at 16 hospitals and clinics. A fear of hypoglycemia was reported by 27.7% of patients. A stepwise logistic regression analysis found that severe hypoglycemia during the past 1 year was a significant determinant of fear of hypoglycemia (odds ratio 2.16, 95% confidence interval 1.06-4.41; P = 0.034), and age (odds ratio 1.02, 95% confidence interval 1.00-1.05, P = 0.038) and living alone (odds ratio 1.93, 95% confidence interval 1.00-3.73, P < 0.05) were significantly higher in patients with fear of hypoglycemia than in those without it.",

author = "Naoki Sakane and Kazuhiko Kotani and Kokoro Tsuzaki and Masami Nishi and Kaoru Takahashi and Takashi Murata and Kazunori Yamada and Kentaro Okazaki and Katsuyuki Yanagisawa and Kenichi Yamada and Nobuichi Kuribayashi and Yasuo Totsuka and Toru Hiyoshi and Motoji Naka and Masatake Sugimoto and Yuji Aoki and Masako Waki and Miyuki Furuya and Haruko Kitaoka and Mariko Oishi and Ikki Shimizu and Hiroaki Miyaoka and Akira Okada and Toshikazu Yamamoto",

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T1 - Fear of hypoglycemia and its determinants in insulin-treated patients with type 2 diabetes mellitus

AU - Sakane, Naoki

AU - Kotani, Kazuhiko

AU - Tsuzaki, Kokoro

AU - Nishi, Masami

AU - Takahashi, Kaoru

AU - Murata, Takashi

AU - Yamada, Kazunori

AU - Okazaki, Kentaro

AU - Yanagisawa, Katsuyuki

AU - Yamada, Kenichi

AU - Kuribayashi, Nobuichi

AU - Totsuka, Yasuo

AU - Hiyoshi, Toru

AU - Naka, Motoji

AU - Sugimoto, Masatake

AU - Aoki, Yuji

AU - Waki, Masako

AU - Furuya, Miyuki

AU - Kitaoka, Haruko

AU - Oishi, Mariko

AU - Shimizu, Ikki

AU - Miyaoka, Hiroaki

AU - Okada, Akira

AU - Yamamoto, Toshikazu

PY - 2015/9/1

Y1 - 2015/9/1

N2 - The aim of the present study was to investigate the prevalence of fear of hypoglycemia, in association with severe hypoglycemia and social factors, in insulin-treated patients with type 2 diabetes mellitus. A questionnaire survey on hypoglycemia and patient-physician communication was carried out in 355 patients with insulin-treated type 2 diabetes mellitus patients at 16 hospitals and clinics. A fear of hypoglycemia was reported by 27.7% of patients. A stepwise logistic regression analysis found that severe hypoglycemia during the past 1 year was a significant determinant of fear of hypoglycemia (odds ratio 2.16, 95% confidence interval 1.06-4.41; P = 0.034), and age (odds ratio 1.02, 95% confidence interval 1.00-1.05, P = 0.038) and living alone (odds ratio 1.93, 95% confidence interval 1.00-3.73, P < 0.05) were significantly higher in patients with fear of hypoglycemia than in those without it.

AB - The aim of the present study was to investigate the prevalence of fear of hypoglycemia, in association with severe hypoglycemia and social factors, in insulin-treated patients with type 2 diabetes mellitus. A questionnaire survey on hypoglycemia and patient-physician communication was carried out in 355 patients with insulin-treated type 2 diabetes mellitus patients at 16 hospitals and clinics. A fear of hypoglycemia was reported by 27.7% of patients. A stepwise logistic regression analysis found that severe hypoglycemia during the past 1 year was a significant determinant of fear of hypoglycemia (odds ratio 2.16, 95% confidence interval 1.06-4.41; P = 0.034), and age (odds ratio 1.02, 95% confidence interval 1.00-1.05, P = 0.038) and living alone (odds ratio 1.93, 95% confidence interval 1.00-3.73, P < 0.05) were significantly higher in patients with fear of hypoglycemia than in those without it.

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Fear of hypoglycemia and its determinants in insulin-treated patients with type 2 diabetes mellitus

Abstract

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