Feasibility study of automated framework for estimating lung tumor locations for target-based patient positioning in stereotactic body radiotherapy

Satoshi Yoshidome, Hidetaka Arimura, Katsumasa Nakamura, Yoshiyuki Shioyama, Kazushige Atsumi, Yasuhiko Nakamura, Hideki Yoshikawa, Kei Nishikawa, Hideki Hirata

Research output: Contribution to journalArticle

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Abstract

Objective. To investigate the feasibility of an automated framework for estimating the lung tumor locations for tumor-based patient positioning with megavolt-cone-beam computed tomography (MV-CBCT) during stereotactic body radiotherapy (SBRT). Methods. A lung screening phantom and ten lung cancer cases with solid lung tumors, who were treated with SBRT, were employed to this study. The locations of tumors in MV-CBCT images were estimated using a tumor-template matching technique between a tumor template and the MV-CBCT. Tumor templates were produced by cropping the gross tumor volume (GTV) regions, which were enhanced by a Sobel filter or a blob structure enhancement (BSE) filter. Reference tumor locations (grand truth) were determined based on a consensus between a radiation oncologist and a medical physicist. Results. According to the results of the phantom study, the average Euclidean distances of the location errors in the original, Sobel-filtered, and BSE-filtered images were 2.0 ± 4.1 mm, 12.8 ± 9.4 mm, and 0.4 ± 0.5 mm, respectively. For clinical cases, these were 3.4 ± 7.1 mm, 7.2 ± 11.6 mm, and 1.6 ± 1.2 mm, respectively. Conclusion. The feasibility study suggests that our proposed framework based on the BSE filter may be a useful tool for tumor-based patient positioning in SBRT.

Original languageEnglish
Article number653974
JournalBioMed Research International
Volume2015
DOIs
Publication statusPublished - Jan 5 2015

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Patient Positioning
Radiosurgery
Radiotherapy
Feasibility Studies
Tumors
Lung
Neoplasms
Cone-Beam Computed Tomography
Tomography
Cones
Image Enhancement
Template matching
Image enhancement
Tumor Burden
Lung Neoplasms
Screening

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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Feasibility study of automated framework for estimating lung tumor locations for target-based patient positioning in stereotactic body radiotherapy. / Yoshidome, Satoshi; Arimura, Hidetaka; Nakamura, Katsumasa; Shioyama, Yoshiyuki; Atsumi, Kazushige; Nakamura, Yasuhiko; Yoshikawa, Hideki; Nishikawa, Kei; Hirata, Hideki.

In: BioMed Research International, Vol. 2015, 653974, 05.01.2015.

Research output: Contribution to journalArticle

Yoshidome, Satoshi ; Arimura, Hidetaka ; Nakamura, Katsumasa ; Shioyama, Yoshiyuki ; Atsumi, Kazushige ; Nakamura, Yasuhiko ; Yoshikawa, Hideki ; Nishikawa, Kei ; Hirata, Hideki. / Feasibility study of automated framework for estimating lung tumor locations for target-based patient positioning in stereotactic body radiotherapy. In: BioMed Research International. 2015 ; Vol. 2015.
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