Feeding behavior in rats fed diets containing medium chain triglyceride

Mitsuhiro Furuse, Yang Ho Choi, Remedios T. Mabayo, Jun Ichi Okumura

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The effect of dietary medium chain triglyceride (MCT) on shortterm food intake was compared with the effect of long chain triglyceride (LCT) in rats. Corn oil and glyceryl tricaprylate were used as LCT and MCT sources, respectively. Rats were given diets containing 200 g MCT/kg diet (MCT diet), 100 g MCT + 100 g LCT/kg diet (ML diet), or 200 g LCT/kg diet (LCT diet) in Experiment 1. Cumulative food intake was determined every h for the first 12 h, then at 2-h intervals thereafter during the subsequent 12 h. As early as 1 h after feeding, cumulative food intake significantly decreased in MCT-fed animals in a dose-dependent fashion. In Experiment 2, rats were given a choice between MCT and LCT diets for 1 h to confirm whether or not the palatability of diets was influenced by dietary fat sources. There was no difference in food intake between the two diets. In Experiment 3, the responsibility of endogenous cholecytokinin (CCK) for the difference in food intake between the two diets was investigated for 6 h by using a CCK-A receptor antagonist, Devazepide (DVZ, 1 mg/kg b. wt.). Food intake in the MCT diet and also in the LCT diet was improved by DVZ. It is concluded that the satiety, but not the palatability, is affected by carbon chain length in dietary triglyceride sources, although the responsibility of endogenous CCK is very small.

Original languageEnglish
Pages (from-to)815-817
Number of pages3
JournalPhysiology and Behavior
Volume52
Issue number4
DOIs
Publication statusPublished - Jan 1 1992
Externally publishedYes

Fingerprint

Feeding Behavior
Triglycerides
Diet
Eating
Devazepide
Corn Oil
Dietary Fats
Carbon

All Science Journal Classification (ASJC) codes

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Cite this

Feeding behavior in rats fed diets containing medium chain triglyceride. / Furuse, Mitsuhiro; Choi, Yang Ho; Mabayo, Remedios T.; Okumura, Jun Ichi.

In: Physiology and Behavior, Vol. 52, No. 4, 01.01.1992, p. 815-817.

Research output: Contribution to journalArticle

Furuse, Mitsuhiro ; Choi, Yang Ho ; Mabayo, Remedios T. ; Okumura, Jun Ichi. / Feeding behavior in rats fed diets containing medium chain triglyceride. In: Physiology and Behavior. 1992 ; Vol. 52, No. 4. pp. 815-817.
@article{d00d90efd5274a658f20c70538696e07,
title = "Feeding behavior in rats fed diets containing medium chain triglyceride",
abstract = "The effect of dietary medium chain triglyceride (MCT) on shortterm food intake was compared with the effect of long chain triglyceride (LCT) in rats. Corn oil and glyceryl tricaprylate were used as LCT and MCT sources, respectively. Rats were given diets containing 200 g MCT/kg diet (MCT diet), 100 g MCT + 100 g LCT/kg diet (ML diet), or 200 g LCT/kg diet (LCT diet) in Experiment 1. Cumulative food intake was determined every h for the first 12 h, then at 2-h intervals thereafter during the subsequent 12 h. As early as 1 h after feeding, cumulative food intake significantly decreased in MCT-fed animals in a dose-dependent fashion. In Experiment 2, rats were given a choice between MCT and LCT diets for 1 h to confirm whether or not the palatability of diets was influenced by dietary fat sources. There was no difference in food intake between the two diets. In Experiment 3, the responsibility of endogenous cholecytokinin (CCK) for the difference in food intake between the two diets was investigated for 6 h by using a CCK-A receptor antagonist, Devazepide (DVZ, 1 mg/kg b. wt.). Food intake in the MCT diet and also in the LCT diet was improved by DVZ. It is concluded that the satiety, but not the palatability, is affected by carbon chain length in dietary triglyceride sources, although the responsibility of endogenous CCK is very small.",
author = "Mitsuhiro Furuse and Choi, {Yang Ho} and Mabayo, {Remedios T.} and Okumura, {Jun Ichi}",
year = "1992",
month = "1",
day = "1",
doi = "10.1016/0031-9384(92)90419-3",
language = "English",
volume = "52",
pages = "815--817",
journal = "Physiology and Behavior",
issn = "0031-9384",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - Feeding behavior in rats fed diets containing medium chain triglyceride

AU - Furuse, Mitsuhiro

AU - Choi, Yang Ho

AU - Mabayo, Remedios T.

AU - Okumura, Jun Ichi

PY - 1992/1/1

Y1 - 1992/1/1

N2 - The effect of dietary medium chain triglyceride (MCT) on shortterm food intake was compared with the effect of long chain triglyceride (LCT) in rats. Corn oil and glyceryl tricaprylate were used as LCT and MCT sources, respectively. Rats were given diets containing 200 g MCT/kg diet (MCT diet), 100 g MCT + 100 g LCT/kg diet (ML diet), or 200 g LCT/kg diet (LCT diet) in Experiment 1. Cumulative food intake was determined every h for the first 12 h, then at 2-h intervals thereafter during the subsequent 12 h. As early as 1 h after feeding, cumulative food intake significantly decreased in MCT-fed animals in a dose-dependent fashion. In Experiment 2, rats were given a choice between MCT and LCT diets for 1 h to confirm whether or not the palatability of diets was influenced by dietary fat sources. There was no difference in food intake between the two diets. In Experiment 3, the responsibility of endogenous cholecytokinin (CCK) for the difference in food intake between the two diets was investigated for 6 h by using a CCK-A receptor antagonist, Devazepide (DVZ, 1 mg/kg b. wt.). Food intake in the MCT diet and also in the LCT diet was improved by DVZ. It is concluded that the satiety, but not the palatability, is affected by carbon chain length in dietary triglyceride sources, although the responsibility of endogenous CCK is very small.

AB - The effect of dietary medium chain triglyceride (MCT) on shortterm food intake was compared with the effect of long chain triglyceride (LCT) in rats. Corn oil and glyceryl tricaprylate were used as LCT and MCT sources, respectively. Rats were given diets containing 200 g MCT/kg diet (MCT diet), 100 g MCT + 100 g LCT/kg diet (ML diet), or 200 g LCT/kg diet (LCT diet) in Experiment 1. Cumulative food intake was determined every h for the first 12 h, then at 2-h intervals thereafter during the subsequent 12 h. As early as 1 h after feeding, cumulative food intake significantly decreased in MCT-fed animals in a dose-dependent fashion. In Experiment 2, rats were given a choice between MCT and LCT diets for 1 h to confirm whether or not the palatability of diets was influenced by dietary fat sources. There was no difference in food intake between the two diets. In Experiment 3, the responsibility of endogenous cholecytokinin (CCK) for the difference in food intake between the two diets was investigated for 6 h by using a CCK-A receptor antagonist, Devazepide (DVZ, 1 mg/kg b. wt.). Food intake in the MCT diet and also in the LCT diet was improved by DVZ. It is concluded that the satiety, but not the palatability, is affected by carbon chain length in dietary triglyceride sources, although the responsibility of endogenous CCK is very small.

UR - http://www.scopus.com/inward/record.url?scp=0026667897&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026667897&partnerID=8YFLogxK

U2 - 10.1016/0031-9384(92)90419-3

DO - 10.1016/0031-9384(92)90419-3

M3 - Article

VL - 52

SP - 815

EP - 817

JO - Physiology and Behavior

JF - Physiology and Behavior

SN - 0031-9384

IS - 4

ER -