TY - JOUR
T1 - Fertilization success and sexual behavior in male medaka, Oryzias latipes, exposed to tributyltin
AU - Nakayama, Kei
AU - Oshima, Yuji
AU - Yamaguchi, Tomomi
AU - Tsuruda, Yukinari
AU - Kang, Ik Joon
AU - Kobayashi, Makito
AU - Imada, Nobuyoshi
AU - Honjo, Tsuneo
N1 - Funding Information:
This study was supported in part by the Special Coordination Funds for Promoting Science and Technology of the Science and Technology Agency of the Japanese Government.
PY - 2004/6
Y1 - 2004/6
N2 - We evaluated the effects of tributyltin (TBT), polychlorinated biphenyls (PCBs), and a mixture of TBT and PCBs on reproduction, gonadal histology, and sexual behavior in Japanese medaka (Oryzias latipes). We administered TBT (1 μgg-1 body weight [b.w.] daily), PCBs (1 μgg-1 b.w. daily), or both to medaka for 3 weeks. We assessed reproductive success during week 3 and the sexual behavior of male medaka after the exposure period. Fertilization success was significantly decreased in groups that received TBT. The profiles of fertility developed a bimodal distribution in the TBT and TBT+PCBs groups, and the numbers of males that performed "following" and "dancing" were significantly decreased in the TBT+PCBs group. The frequency of "dancing" also decreased after treatment with TBT, whereas fish that received PCBs only showed no difference in sexual behavior. Testes that had oocytes showed normal spermatogenesis, even though two of the five males treated with TBT+PCBs had some indication of testis-ova, which did not occur in any other group. Our results indicate that TBT, but not PCBs, affects sexual behavior and reproduction in medaka.
AB - We evaluated the effects of tributyltin (TBT), polychlorinated biphenyls (PCBs), and a mixture of TBT and PCBs on reproduction, gonadal histology, and sexual behavior in Japanese medaka (Oryzias latipes). We administered TBT (1 μgg-1 body weight [b.w.] daily), PCBs (1 μgg-1 b.w. daily), or both to medaka for 3 weeks. We assessed reproductive success during week 3 and the sexual behavior of male medaka after the exposure period. Fertilization success was significantly decreased in groups that received TBT. The profiles of fertility developed a bimodal distribution in the TBT and TBT+PCBs groups, and the numbers of males that performed "following" and "dancing" were significantly decreased in the TBT+PCBs group. The frequency of "dancing" also decreased after treatment with TBT, whereas fish that received PCBs only showed no difference in sexual behavior. Testes that had oocytes showed normal spermatogenesis, even though two of the five males treated with TBT+PCBs had some indication of testis-ova, which did not occur in any other group. Our results indicate that TBT, but not PCBs, affects sexual behavior and reproduction in medaka.
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U2 - 10.1016/j.chemosphere.2003.11.050
DO - 10.1016/j.chemosphere.2003.11.050
M3 - Article
C2 - 15081776
AN - SCOPUS:1842636940
SN - 0045-6535
VL - 55
SP - 1331
EP - 1337
JO - Chemosphere
JF - Chemosphere
IS - 10
ER -