Fibronectin of the chorioretinal interface in the monkey: immunohistochemical and immunoelectron microscopic studies

Tatsuro Ishibashi, Toshihiko Kohno, Nino Sorgente, Randi Patterson, Stephen J. Ryan

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

The distribution of fibronectin in the chorioretinal interface of the monkey eye was studied by indirect immunofluorescent and immunoelectron microscopic techniques. Immunofluorescent staining revealed fibronectin in Bruch's membrane and the choriocapillaris. Immunoelectron microscopic techniques revealed fibronectin associated with basement membranes, collagen fibers and elastic fibers in Bruch's membrane; the stromal side of the basement membrane of the choriocapillaris also showed staining. This study thus demonstrates that fibronectin is an integral component of Bruch's membrane in the monkey eye.

Original languageEnglish
Pages (from-to)158-163
Number of pages6
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume223
Issue number3
DOIs
Publication statusPublished - Jul 1985
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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