The first fluorescent chemosensors toward a native phosphorylated peptide are successfully synthesized. Dinuclear zinc(II)-dipicolylamine-based anthracene (1, 2) can selectively recognize and sense phosphorylated species with an increase in the fluorescence intensity. We also demonstrated that these artificial receptors fluorometrically detect a phosphorylated peptide with high affinity (≥ 107 M-1) in aqueous solution.
|Number of pages||3|
|Journal||Journal of the American Chemical Society|
|Publication status||Published - Jun 5 2002|
All Science Journal Classification (ASJC) codes
- Colloid and Surface Chemistry