Flavin-trapping of the transient enediolate species formed during glyoxalase I catalysis

Kaori Ueda, Seiji Shinkai, Kenneth T. Douglas

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A reactive intermediate, probably an enediolate species, has been oxidatively trapped by reaction with added flavin during catalytic turnover by yeast glyoxalase I of the thiohemiacetal from glutathione and phenylglyoxal under anaerobic conditions.

Original languageEnglish
Pages (from-to)371-372
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number6
DOIs
Publication statusPublished - Jan 1 1984
Externally publishedYes

Fingerprint

Phenylglyoxal
Lactoylglutathione Lyase
Catalysis
Yeast
Glutathione
Yeasts
4,6-dinitro-o-cresol

All Science Journal Classification (ASJC) codes

  • Molecular Medicine

Cite this

Flavin-trapping of the transient enediolate species formed during glyoxalase I catalysis. / Ueda, Kaori; Shinkai, Seiji; Douglas, Kenneth T.

In: Journal of the Chemical Society, Chemical Communications, No. 6, 01.01.1984, p. 371-372.

Research output: Contribution to journalArticle

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