Flavonoids with free radical scavenging activity and nitric oxide inhibitory effect from the stem bark of Artocarpus gomezianus

B. Sritularak, A. Tantituvanont, P. Chanvorachote, K. Meksawan, T. Miyamoto, Y. Kohno, K. Likhitwitayawuid

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

A MeOH extract from the stem bark of Artocarpus gomezianus showed DPPH free radical scavenging activity. Bio-assay guided fractionation of this MeOH extract led to the isolation of four flavonoids, namely artonin E (1), cycloartobiloxanthone (2), artobiloxanthone (3) and (+)-catechin (4). These compounds were shown to possess recognizable DPPH free radical scavenging activity and appreciable inhibitory effect on nitric oxide production in murine macrophage-like cells.

Original languageEnglish
Pages (from-to)387-392
Number of pages6
JournalJournal of Medicinal Plants Research
Volume4
Issue number5
Publication statusPublished - Mar 4 2010

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

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