@article{b9835bc5317f4878b258b57b48f46000,
title = "Fluorescence detection of metabolic activity of the fatty acid beta oxidation pathway in living cells",
abstract = "Detection of metabolic activity in living cells facilitates the understanding of the cell mechanism. Here, we report a fluorescent probe that can detect fatty acid beta oxidation (FAO) in living cells. This probe is metabolically degraded by the sequential enzyme reactions of FAO and can visualize the FAO activity with turn-on fluorescence.",
author = "Shohei Uchinomiya and Naoya Matsunaga and Koichiro Kamoda and Ryosuke Kawagoe and Akito Tsuruta and Shigehiro Ohdo and Akio Ojida",
note = "Funding Information: We appreciate the technical assistance from The Research Support Center, Research Center for Human Disease Modeling, Kyushu University Graduate School of Medical Sciences. This work was supported by a Grant-in-Aid for Scientific Research on Innovative Areas {\textquoteleft}{\textquoteleft}Chemistry for Multimolecular Crowding Biosystems{\textquoteright}{\textquoteright} (JSPS KAKENHI Grant No. JP17H06349), Grant-in-Aid for Challenging Exploratory Research (JSPS KAKENHI Grant No. JP17K19203), and Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)) from AMED under Grant Number JP18am0101091. A.O. acknowledges Naito Science Foundation and Toray Science Foundation for their financial supports. S.U. acknowledges Grant-in-Aid for Young Scientists B (JSPS KAKENHI Grant No. JP17K14518) for its financial support. Publisher Copyright: {\textcopyright} 2020 The Royal Society of Chemistry.",
year = "2020",
month = mar,
day = "11",
doi = "10.1039/c9cc09993j",
language = "English",
volume = "56",
pages = "3023--3026",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "20",
}