Fluorescence detection of metabolic activity of the fatty acid beta oxidation pathway in living cells

Shohei Uchinomiya, Naoya Matsunaga, Koichiro Kamoda, Ryosuke Kawagoe, Akito Tsuruta, Shigehiro Ohdo, Akio Ojida

Research output: Contribution to journalArticle

Abstract

Detection of metabolic activity in living cells facilitates the understanding of the cell mechanism. Here, we report a fluorescent probe that can detect fatty acid beta oxidation (FAO) in living cells. This probe is metabolically degraded by the sequential enzyme reactions of FAO and can visualize the FAO activity with turn-on fluorescence.

Original languageEnglish
Pages (from-to)3023-3026
Number of pages4
JournalChemical Communications
Volume56
Issue number20
DOIs
Publication statusPublished - Mar 11 2020

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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