Fluorescence Sensing of Inorganic Phosphate and Pyrophosphate Using Small Molecular Sensors and Their Applications

Jirarut Wongkongkatep, Akio Ojida, Itaru Hamachi

Research output: Contribution to journalReview articlepeer-review

20 Citations (Scopus)

Abstract

The aim of this contribution is to provide an introduction and a brief summary of the principle of fluorescence molecular sensors specific to inorganic phosphate (Pi) and inorganic pyrophosphate (PPi) as well as their applications. In our introduction we describe the impact of both Pi and PPi in the living organism and in the environment, followed by a description of the principle of fluorescence molecular sensors and the sensing mechanism in solution. We then focus on exciting research which has emerged in recent years on the development of fluorescent sensors specific to Pi and PPi, categorized by chemical interactions between the sensor and the target molecule, such as hydrogen bonding, coordination chemistry, displacement assay, aggregation induced emission or quenching, and chemical reactions.

Original languageEnglish
Article number30
JournalTopics in Current Chemistry
Volume375
Issue number2
DOIs
Publication statusPublished - Apr 1 2017

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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