Fluorine-18-fluorodeoxyglucose positron emission tomography in technetium- 99m-hydroxymethylenediphosphate negative bone tumors

M. Sasaki, Y. Ichiya, Y. Kuwabara, M. Otsuka, T. Fukumura, Y. Kawai, H. Koga, K. Masuda

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

We have encountered two cases of bone tumors with high 18F- fluorodeoxyglucose (FDG) uptake and negative 99mTc-HMDP bone scintigraphy, including a patient with myeloma and a patient with a metastatic bone tumor from esophageal cancer. Bone scintigraphy with a 99mTc-phosphate complex reflects osteoblastic activity in the bone tissue surrounding the tumor, whereas the accumulation of FDG is associated with the metabolic activity of the tumor itself. An FDG-PET study can therefore be used as a complementary study for the detection and follow-up of bone tumors when a 99mTc- phosphate bone scintigram is negative.

Original languageEnglish
Pages (from-to)288-290
Number of pages3
JournalJournal of Nuclear Medicine
Volume34
Issue number2
Publication statusPublished - Jan 1 1993

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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