We have encountered two cases of bone tumors with high 18F- fluorodeoxyglucose (FDG) uptake and negative 99mTc-HMDP bone scintigraphy, including a patient with myeloma and a patient with a metastatic bone tumor from esophageal cancer. Bone scintigraphy with a 99mTc-phosphate complex reflects osteoblastic activity in the bone tissue surrounding the tumor, whereas the accumulation of FDG is associated with the metabolic activity of the tumor itself. An FDG-PET study can therefore be used as a complementary study for the detection and follow-up of bone tumors when a 99mTc- phosphate bone scintigram is negative.
|Number of pages||3|
|Journal||Journal of Nuclear Medicine|
|Publication status||Published - Jan 1 1993|
All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging