Fluorine-18-fluorodeoxyglucose positron emission tomography in technetium- 99m-hydroxymethylenediphosphate negative bone tumors

M. Sasaki, Y. Ichiya, Y. Kuwabara, M. Otsuka, T. Fukumura, Y. Kawai, H. Koga, K. Masuda

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Abstract

We have encountered two cases of bone tumors with high 18F- fluorodeoxyglucose (FDG) uptake and negative 99mTc-HMDP bone scintigraphy, including a patient with myeloma and a patient with a metastatic bone tumor from esophageal cancer. Bone scintigraphy with a 99mTc-phosphate complex reflects osteoblastic activity in the bone tissue surrounding the tumor, whereas the accumulation of FDG is associated with the metabolic activity of the tumor itself. An FDG-PET study can therefore be used as a complementary study for the detection and follow-up of bone tumors when a 99mTc- phosphate bone scintigram is negative.

Original languageEnglish
Pages (from-to)288-290
Number of pages3
JournalJournal of Nuclear Medicine
Volume34
Issue number2
Publication statusPublished - Jan 1 1993

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Technetium
Fluorodeoxyglucose F18
Positron-Emission Tomography
Bone and Bones
Neoplasms
Radionuclide Imaging
Phosphates
Esophageal Neoplasms

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Fluorine-18-fluorodeoxyglucose positron emission tomography in technetium- 99m-hydroxymethylenediphosphate negative bone tumors. / Sasaki, M.; Ichiya, Y.; Kuwabara, Y.; Otsuka, M.; Fukumura, T.; Kawai, Y.; Koga, H.; Masuda, K.

In: Journal of Nuclear Medicine, Vol. 34, No. 2, 01.01.1993, p. 288-290.

Research output: Contribution to journalArticle

Sasaki, M, Ichiya, Y, Kuwabara, Y, Otsuka, M, Fukumura, T, Kawai, Y, Koga, H & Masuda, K 1993, 'Fluorine-18-fluorodeoxyglucose positron emission tomography in technetium- 99m-hydroxymethylenediphosphate negative bone tumors', Journal of Nuclear Medicine, vol. 34, no. 2, pp. 288-290.
Sasaki, M. ; Ichiya, Y. ; Kuwabara, Y. ; Otsuka, M. ; Fukumura, T. ; Kawai, Y. ; Koga, H. ; Masuda, K. / Fluorine-18-fluorodeoxyglucose positron emission tomography in technetium- 99m-hydroxymethylenediphosphate negative bone tumors. In: Journal of Nuclear Medicine. 1993 ; Vol. 34, No. 2. pp. 288-290.
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