Fluorine-18-fluorodeoxyglucose positron emission tomography in technetium- 99m-hydroxymethylenediphosphate negative bone tumors

M. Sasaki; Y. Ichiya; Y. Kuwabara; M. Otsuka; T. Fukumura; Y. Kawai; H. Koga; K. Masuda

Fluorine-18-fluorodeoxyglucose positron emission tomography in technetium- 99m-hydroxymethylenediphosphate negative bone tumors

M. Sasaki, Y. Ichiya, Y. Kuwabara, M. Otsuka, T. Fukumura, Y. Kawai, H. Koga, K. Masuda

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Abstract

We have encountered two cases of bone tumors with high ¹⁸F- fluorodeoxyglucose (FDG) uptake and negative ^99mTc-HMDP bone scintigraphy, including a patient with myeloma and a patient with a metastatic bone tumor from esophageal cancer. Bone scintigraphy with a ^99mTc-phosphate complex reflects osteoblastic activity in the bone tissue surrounding the tumor, whereas the accumulation of FDG is associated with the metabolic activity of the tumor itself. An FDG-PET study can therefore be used as a complementary study for the detection and follow-up of bone tumors when a ^99mTc- phosphate bone scintigram is negative.

Original language	English
Pages (from-to)	288-290
Number of pages	3
Journal	Journal of Nuclear Medicine
Volume	34
Issue number	2
Publication status	Published - Jan 1 1993

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

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title = "Fluorine-18-fluorodeoxyglucose positron emission tomography in technetium- 99m-hydroxymethylenediphosphate negative bone tumors",

abstract = "We have encountered two cases of bone tumors with high 18F- fluorodeoxyglucose (FDG) uptake and negative 99mTc-HMDP bone scintigraphy, including a patient with myeloma and a patient with a metastatic bone tumor from esophageal cancer. Bone scintigraphy with a 99mTc-phosphate complex reflects osteoblastic activity in the bone tissue surrounding the tumor, whereas the accumulation of FDG is associated with the metabolic activity of the tumor itself. An FDG-PET study can therefore be used as a complementary study for the detection and follow-up of bone tumors when a 99mTc- phosphate bone scintigram is negative.",

author = "M. Sasaki and Y. Ichiya and Y. Kuwabara and M. Otsuka and T. Fukumura and Y. Kawai and H. Koga and K. Masuda",

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AU - Sasaki, M.

AU - Ichiya, Y.

AU - Kuwabara, Y.

AU - Otsuka, M.

AU - Fukumura, T.

AU - Kawai, Y.

AU - Koga, H.

AU - Masuda, K.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - We have encountered two cases of bone tumors with high 18F- fluorodeoxyglucose (FDG) uptake and negative 99mTc-HMDP bone scintigraphy, including a patient with myeloma and a patient with a metastatic bone tumor from esophageal cancer. Bone scintigraphy with a 99mTc-phosphate complex reflects osteoblastic activity in the bone tissue surrounding the tumor, whereas the accumulation of FDG is associated with the metabolic activity of the tumor itself. An FDG-PET study can therefore be used as a complementary study for the detection and follow-up of bone tumors when a 99mTc- phosphate bone scintigram is negative.

AB - We have encountered two cases of bone tumors with high 18F- fluorodeoxyglucose (FDG) uptake and negative 99mTc-HMDP bone scintigraphy, including a patient with myeloma and a patient with a metastatic bone tumor from esophageal cancer. Bone scintigraphy with a 99mTc-phosphate complex reflects osteoblastic activity in the bone tissue surrounding the tumor, whereas the accumulation of FDG is associated with the metabolic activity of the tumor itself. An FDG-PET study can therefore be used as a complementary study for the detection and follow-up of bone tumors when a 99mTc- phosphate bone scintigram is negative.

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Fluorine-18-fluorodeoxyglucose positron emission tomography in technetium- 99m-hydroxymethylenediphosphate negative bone tumors

Abstract

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