Follicular dendritic cell sarcoma of the neck; a case report and literature review

Torahiko Nakashima, Yuichiro Kuratomi, Hideki Shiratsuchi, Hidetaka Yamamoto, Ryuji Yasumatsu, Tomoya Yamamoto, Sohtaro Komiyama

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Follicular dendritic cell (FDC) sarcomas, also known as dendritic reticulum cell tumors, are uncommon neoplasms arising from antigen-presenting cells in B-lymphofollicles of nodal and extra-nodal sites. It is considered as an intermediate grade malignancy since it has significant recurrent and metastatic potential. We report a case of FDC sarcoma arising in the neck. A 56-year-old female presented with a left neck tumor. Neck dissection was performed. Microscopically, the tumor showed spindle-shaped stromal cells with large oval and polygonal nuclei. Immunohistologically, the cells were positive for CD21 and CD35, consistent with FDC sarcomas. Adjuvant chemotherapy of cyclophosphamide/doxorubicin/vincristine/prednisone (CHOP) was given. Literature review provides the current information for the diagnosis and treatment of this unusual tumor.

Original languageEnglish
Pages (from-to)401-403
Number of pages3
JournalAuris Nasus Larynx
Volume29
Issue number4
DOIs
Publication statusPublished - Oct 1 2002

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

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