Follicular dendritic cell sarcoma of the neck; a case report and literature review

Torahiko Nakashima, Yuichiro Kuratomi, Hideki Shiratsuchi, Hidetaka Yamamoto, Ryuji Yasumatsu, Tomoya Yamamoto, Sohtaro Komiyama

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Follicular dendritic cell (FDC) sarcomas, also known as dendritic reticulum cell tumors, are uncommon neoplasms arising from antigen-presenting cells in B-lymphofollicles of nodal and extra-nodal sites. It is considered as an intermediate grade malignancy since it has significant recurrent and metastatic potential. We report a case of FDC sarcoma arising in the neck. A 56-year-old female presented with a left neck tumor. Neck dissection was performed. Microscopically, the tumor showed spindle-shaped stromal cells with large oval and polygonal nuclei. Immunohistologically, the cells were positive for CD21 and CD35, consistent with FDC sarcomas. Adjuvant chemotherapy of cyclophosphamide/doxorubicin/vincristine/prednisone (CHOP) was given. Literature review provides the current information for the diagnosis and treatment of this unusual tumor.

Original languageEnglish
Pages (from-to)401-403
Number of pages3
JournalAuris Nasus Larynx
Volume29
Issue number4
DOIs
Publication statusPublished - Oct 1 2002

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Follicular Dendritic Cell Sarcoma
Neck
Neoplasms
Reticulum
Neck Dissection
Vincristine
Neoplasm Antigens
Antigen-Presenting Cells
Adjuvant Chemotherapy
Stromal Cells
Prednisone
Doxorubicin
Cyclophosphamide
Dendritic Cells

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

Cite this

Follicular dendritic cell sarcoma of the neck; a case report and literature review. / Nakashima, Torahiko; Kuratomi, Yuichiro; Shiratsuchi, Hideki; Yamamoto, Hidetaka; Yasumatsu, Ryuji; Yamamoto, Tomoya; Komiyama, Sohtaro.

In: Auris Nasus Larynx, Vol. 29, No. 4, 01.10.2002, p. 401-403.

Research output: Contribution to journalArticle

Nakashima, Torahiko ; Kuratomi, Yuichiro ; Shiratsuchi, Hideki ; Yamamoto, Hidetaka ; Yasumatsu, Ryuji ; Yamamoto, Tomoya ; Komiyama, Sohtaro. / Follicular dendritic cell sarcoma of the neck; a case report and literature review. In: Auris Nasus Larynx. 2002 ; Vol. 29, No. 4. pp. 401-403.
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