Force sensor probe using quartz crystal resonator having104 measurement range for mechanical characterization of spheroids

Ayaka Sato, Shinya Sakuma, Nobuhiko Kojima, Fumiya Tao, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Recently, evaluation of biological activity of spheroids without dissolution is quite important. In this study, we focus on a force sensor for mechanical characterization of spheroids. The force sensor probe which has wide measurement range is highly required for evaluating stiffness of spheroid in medium environment because spheroid has nonlinear mechanical characteristics. Herein, we present a force sensor probe using quartz crystal resonator (QCR). The proposed force sensor probe has wide measurement range of 104 and waterproof structure. We evaluated its performance and mechanical characterization of HepG2 spheroids by using the proposed force sensor probe.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages1382-1383
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Externally publishedYes
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: Oct 9 2016Oct 13 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period10/9/1610/13/16

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

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