Forensic analysis of triazolam in human tissues using capillary gas chromatography

K. Kudo, T. Nagata, T. Imamura, S. Kage, Y. Hida

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A reliable and sensitive method has been developed to assess the concentrations of the hypnotic drug triazolam in human tissues, including putrefied tissues. The method involves a 3-step solvent extraction, cleanup on a silica gel column and gas chromatography using a nitrogen phosphorus detector and a capillary column. Estazolam was used as an internal standard. The calibration curve was linear over the concentration range 1 ng/g1 gm/g and the lower limit of detection was 0.5 ng/g. A forensic study was performed on the toxicological effects of triazolam using putrefied tissues.

Original languageEnglish
Pages (from-to)67-69
Number of pages3
JournalInternational Journal of Legal Medicine
Volume104
Issue number2
DOIs
Publication statusPublished - Mar 1 1991

Fingerprint

Triazolam
Gas Chromatography
Estazolam
Silica Gel
Hypnotics and Sedatives
Toxicology
Phosphorus
Calibration
Gel Chromatography
Limit of Detection
Nitrogen
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

Forensic analysis of triazolam in human tissues using capillary gas chromatography. / Kudo, K.; Nagata, T.; Imamura, T.; Kage, S.; Hida, Y.

In: International Journal of Legal Medicine, Vol. 104, No. 2, 01.03.1991, p. 67-69.

Research output: Contribution to journalArticle

Kudo, K. ; Nagata, T. ; Imamura, T. ; Kage, S. ; Hida, Y. / Forensic analysis of triazolam in human tissues using capillary gas chromatography. In: International Journal of Legal Medicine. 1991 ; Vol. 104, No. 2. pp. 67-69.
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