TY - JOUR
T1 - Frailty in patients with abdominal aortic aneurysm predicts prognosis after elective endovascular aneurysm repair
AU - Morisaki, Koichi
AU - Furuyama, Tadashi
AU - Yoshiya, Keiji
AU - Kurose, Shun
AU - Yoshino, Shinichiro
AU - Nakayama, Ken
AU - Yamashita, Sho
AU - Kawakubo, Eisuke
AU - Matsumoto, Takuya
AU - Mori, Masaki
N1 - Funding Information:
We thank Jane Charbonneau, DVM, from Edanz Group (https://jp.edanzgroup.com/) for editing a draft of the manuscript.
PY - 2020/7
Y1 - 2020/7
N2 - Objective: The diagnostic criteria for frailty in patients with abdominal aortic aneurysm (AAA) are undefined. Our purpose was to examine the influence of new diagnostic criteria for frailty on overall survival after endovascular aneurysm repair (EVAR). Methods: We retrospectively analyzed data for patients undergoing EVAR between 2007 and 2015. Isolated common iliac artery aneurysm and ruptured AAA were excluded. Patients were defined as having frailty when they had at least two of low Geriatric Nutritional Risk Index, sarcopenia, or nonambulatory status. We examined whether frailty affected overall survival, postoperative complications, and reintervention. Results: Over the study period, 349 patients underwent EVAR. Thirty-three patients were excluded. The 5-year overall survival after EVAR was 76.7% for the frailty-negative group vs 43.1% for the frailty-positive group (P <.01). Age, frailty-positive status, and current cancer therapy were risk factors for overall survival. Positive frailty was the only risk factor for postoperative complications. Forty-two patients underwent reintervention. Outside instructions for use was a risk factor for reintervention after EVAR. Conclusions: Assessing frailty in patients with AAA is useful for determining risk factors for 5-year overall survival and postoperative complications.
AB - Objective: The diagnostic criteria for frailty in patients with abdominal aortic aneurysm (AAA) are undefined. Our purpose was to examine the influence of new diagnostic criteria for frailty on overall survival after endovascular aneurysm repair (EVAR). Methods: We retrospectively analyzed data for patients undergoing EVAR between 2007 and 2015. Isolated common iliac artery aneurysm and ruptured AAA were excluded. Patients were defined as having frailty when they had at least two of low Geriatric Nutritional Risk Index, sarcopenia, or nonambulatory status. We examined whether frailty affected overall survival, postoperative complications, and reintervention. Results: Over the study period, 349 patients underwent EVAR. Thirty-three patients were excluded. The 5-year overall survival after EVAR was 76.7% for the frailty-negative group vs 43.1% for the frailty-positive group (P <.01). Age, frailty-positive status, and current cancer therapy were risk factors for overall survival. Positive frailty was the only risk factor for postoperative complications. Forty-two patients underwent reintervention. Outside instructions for use was a risk factor for reintervention after EVAR. Conclusions: Assessing frailty in patients with AAA is useful for determining risk factors for 5-year overall survival and postoperative complications.
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U2 - 10.1016/j.jvs.2019.09.052
DO - 10.1016/j.jvs.2019.09.052
M3 - Article
C2 - 31882319
AN - SCOPUS:85076831674
VL - 72
SP - 138
EP - 143
JO - Journal of Vascular Surgery
JF - Journal of Vascular Surgery
SN - 0741-5214
IS - 1
ER -