From solutions to surfaces: A novel molecular imprinting method based on the conformational changes of boronic-acid-appended poly(L-lysine)

Arianna Friggeri, Hideki Kobayashi, Seiji Shinkai, David N. Reinhoudt

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The dominant solution-phase conformation of a polymer can be fixed to a surface (see scheme). Boronic acid appended poly(L-lysine) assumes different conformations in the presence of D-glucose or D-fructose. When the polymer-glucose complex is anchored to a gold surface, an imprinted interface with "molecular memory" for glucose over fructose can be prepared.

Original languageEnglish
Pages (from-to)4729-4731
Number of pages3
JournalAngewandte Chemie - International Edition
Volume40
Issue number24
DOIs
Publication statusPublished - Dec 17 2001
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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