Functional imaging in periventricular nodular heterotopia with the use of FDG-PET and HMPAO-SPECT

Takato Morioka, Shunji Nishio, Masayuki Sasaki, Tsuyoshi Yoshida, Yasuo Kuwabara, Michiya Ohta, Masashi Fukui

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

We analyzed the interictal [18F]fluoro-2-deoxy-D-glucose positron emission tomography (FGD-PET) and single photon emission computed tomography with technetium-99m-hexamethyl-propyleneamine oxime (HMPAO-SPECT) in two epileptic patients with periventricular nodular heterotopia (PNH). In both cases, we found both the glucose metabolism and the perfusion of PNH to be almost identical to those of the normal cerebral cortex. The metabolic activity and perfusion in the heterotopic gray matter in a subependymal white matter area probably represent the glucose metabolism and perfusion of the abnormally located gray matter rather than a subclinical ictal phenomenon. FDG-PET and HMPAO-SPECT were thus found to be a useful complement to magnetic resonance imaging in the evaluation of PNH.

Original languageEnglish
Pages (from-to)41-44
Number of pages4
JournalNeurosurgical Review
Volume22
Issue number1
DOIs
Publication statusPublished - Apr 1999

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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