Functional regulation of biomolecule using DNA-conjugation.

Takahisa Anada, Takeshi Kano, Wataru Kaku, Yoshiki Katayama, Mizuo Maeda, Masaharu Murata

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

3'-methacryloyl-oligodeoxynucleotide having antisense sequence against messenger RNA of green fluorescent protein and N-isopropylacrylamide were co-polymerized. The conjugate can reversibly change its conformation at around a transition temperature, similarly to N-isopropylacrylamide homopolymer. We achieved artificially regulation of gene expression depending on temperature using the conjugate.

Original languageEnglish
Pages (from-to)269-270
Number of pages2
JournalNucleic acids research. Supplement (2001)
Issue number2
Publication statusPublished - Jan 1 2002

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Transition Temperature
Oligodeoxyribonucleotides
DNA
Gene Expression Regulation
Green Fluorescent Proteins
Messenger RNA
Temperature
N-isopropylacrylamide

Cite this

Functional regulation of biomolecule using DNA-conjugation. / Anada, Takahisa; Kano, Takeshi; Kaku, Wataru; Katayama, Yoshiki; Maeda, Mizuo; Murata, Masaharu.

In: Nucleic acids research. Supplement (2001), No. 2, 01.01.2002, p. 269-270.

Research output: Contribution to journalArticle

Anada, Takahisa ; Kano, Takeshi ; Kaku, Wataru ; Katayama, Yoshiki ; Maeda, Mizuo ; Murata, Masaharu. / Functional regulation of biomolecule using DNA-conjugation. In: Nucleic acids research. Supplement (2001). 2002 ; No. 2. pp. 269-270.
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