Abstract
The unique folding and assembling properties of DNA have been elaborated to construct various nanomachines that can be reversibly switched between two or more distinct conformations. For better applications and developments of DNA nanomachines, their responding outputs and sequence-selectivity need to be improved. Here we show that a simple addition of a cationic comb-type copolymer, poly(L-lysine)-graft-dextran, produces robust and quick responses of DNA-fueled nanomachines under moderate conditions including physiologically relevant conditions through hybrid stabilization and DNA strand exchange acceleration.
| Original language | English |
|---|---|
| Title of host publication | 55th SPSJ Symposium on Macromolecules |
| Pages | 5272-5273 |
| Number of pages | 2 |
| Volume | 55 |
| Edition | 2 |
| Publication status | Published - 2006 |
| Event | 55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: Sep 20 2006 → Sep 22 2006 |
Other
| Other | 55th Society of Polymer Science Japan Symposium on Macromolecules |
|---|---|
| Country | Japan |
| City | Toyama |
| Period | 9/20/06 → 9/22/06 |
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All Science Journal Classification (ASJC) codes
- Engineering(all)
Cite this
Functional regulation of DNA nanomachine by artificial nucleic acid chaperon. / Choi, Sung Won; Makita, Naoki; Kano, Arihiro; Yamayoshi, Asako; Akaike, Toshihiro; Maruyama, Atsushi.
55th SPSJ Symposium on Macromolecules. Vol. 55 2. ed. 2006. p. 5272-5273.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Functional regulation of DNA nanomachine by artificial nucleic acid chaperon
AU - Choi, Sung Won
AU - Makita, Naoki
AU - Kano, Arihiro
AU - Yamayoshi, Asako
AU - Akaike, Toshihiro
AU - Maruyama, Atsushi
PY - 2006
Y1 - 2006
N2 - The unique folding and assembling properties of DNA have been elaborated to construct various nanomachines that can be reversibly switched between two or more distinct conformations. For better applications and developments of DNA nanomachines, their responding outputs and sequence-selectivity need to be improved. Here we show that a simple addition of a cationic comb-type copolymer, poly(L-lysine)-graft-dextran, produces robust and quick responses of DNA-fueled nanomachines under moderate conditions including physiologically relevant conditions through hybrid stabilization and DNA strand exchange acceleration.
AB - The unique folding and assembling properties of DNA have been elaborated to construct various nanomachines that can be reversibly switched between two or more distinct conformations. For better applications and developments of DNA nanomachines, their responding outputs and sequence-selectivity need to be improved. Here we show that a simple addition of a cationic comb-type copolymer, poly(L-lysine)-graft-dextran, produces robust and quick responses of DNA-fueled nanomachines under moderate conditions including physiologically relevant conditions through hybrid stabilization and DNA strand exchange acceleration.
UR - http://www.scopus.com/inward/record.url?scp=33846130085&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33846130085&partnerID=8YFLogxK
M3 - Conference contribution
VL - 55
SP - 5272
EP - 5273
BT - 55th SPSJ Symposium on Macromolecules
ER -